High throughput techniques for the investigation of cell-material interactions

Lauren R. Clements, Helmut Thissen, Nicolas H. Voelcker

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Abstract

The evaluation and control of the cellular response to substrate materials is important for a wide range of regenerative medicine applications including implants, biomaterial devices and biosensors. Gradient surfaces provide a simple and fast method for determining optimal surface conditions for cellular responses such as attachment and growth. This chapter presents an overview of high-throughput techniques available for the optimisation of cell material interactions with particular emphasis on surface topographical and chemical gradients. The gradient approaches presented throughout this chapter are expected to become useful tools for researchers that are aiming to optimise advanced materials for a variety of biomedical applications.
Original languageEnglish
Title of host publicationBiointerfaces
Subtitle of host publicationWhere Material Meets Biology
EditorsDietmar Hutmacher, Wojciech Chrzanowski
Place of PublicationCambridge UK
PublisherThe Royal Society of Chemistry
Chapter10
Pages259-311
Number of pages53
ISBN (Electronic)9781782628453
ISBN (Print)9781849738767
DOIs
Publication statusPublished - 2015
Externally publishedYes

Publication series

NameRSC Smart Materials
PublisherThe Royal Society of Chemistry
Number10
ISSN (Print)2046-0066

Cite this

Clements, L. R., Thissen, H., & Voelcker, N. H. (2015). High throughput techniques for the investigation of cell-material interactions. In D. Hutmacher, & W. Chrzanowski (Eds.), Biointerfaces: Where Material Meets Biology (pp. 259-311). (RSC Smart Materials; No. 10). Cambridge UK: The Royal Society of Chemistry. https://doi.org/10.1039/9781782628453-00257
Clements, Lauren R. ; Thissen, Helmut ; Voelcker, Nicolas H. / High throughput techniques for the investigation of cell-material interactions. Biointerfaces: Where Material Meets Biology. editor / Dietmar Hutmacher ; Wojciech Chrzanowski. Cambridge UK : The Royal Society of Chemistry, 2015. pp. 259-311 (RSC Smart Materials; 10).
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Clements, LR, Thissen, H & Voelcker, NH 2015, High throughput techniques for the investigation of cell-material interactions. in D Hutmacher & W Chrzanowski (eds), Biointerfaces: Where Material Meets Biology. RSC Smart Materials, no. 10, The Royal Society of Chemistry, Cambridge UK, pp. 259-311. https://doi.org/10.1039/9781782628453-00257

High throughput techniques for the investigation of cell-material interactions. / Clements, Lauren R.; Thissen, Helmut; Voelcker, Nicolas H.

Biointerfaces: Where Material Meets Biology. ed. / Dietmar Hutmacher; Wojciech Chrzanowski. Cambridge UK : The Royal Society of Chemistry, 2015. p. 259-311 (RSC Smart Materials; No. 10).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

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Clements LR, Thissen H, Voelcker NH. High throughput techniques for the investigation of cell-material interactions. In Hutmacher D, Chrzanowski W, editors, Biointerfaces: Where Material Meets Biology. Cambridge UK: The Royal Society of Chemistry. 2015. p. 259-311. (RSC Smart Materials; 10). https://doi.org/10.1039/9781782628453-00257