High resolution chemical mapping of biomimetic membranes by force volume imaging

Matthew R. Nussio, Nicolas H. Voelcker, Matthew J. Sykes, Ben S. Flavel, John O. Miners, Joseph G. Shapter

Research output: Chapter in Book/Report/Conference proceedingConference PaperOtherpeer-review

1 Citation (Scopus)


The analysis of membrane domain segregation and phase separation is of significant interest for the understanding of cell membranes. In this paper, we report a new approach to atomic force microscopy (AFM) of artificial membranes, using both functionalised AFM tips and "Force Volume" AFM imaging for the analysis of membrane phase separation. Simultaneous topology and mapping of interaction forces of binary component phospholipid bilayer membranes was performed yielding novel insights into membrane structure at unprecedented resolution.

Original languageEnglish
Title of host publicationProceedings of the 2008 International Conference on Nanoscience and Nanotechnology, ICONN 2008
Number of pages4
Publication statusPublished - 24 Nov 2008
Externally publishedYes
EventInternational Conference on Nanoscience and Nanotechnology (ICONN) 2008 - Melbourne Convention Centre, Melbourne, Australia
Duration: 25 Feb 200829 Feb 2008
Conference number: 2nd


ConferenceInternational Conference on Nanoscience and Nanotechnology (ICONN) 2008
Abbreviated titleICONN 2008


  • Force-volume
  • Microscopy
  • Phospholipids

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