High-grade B-cell lymphoma relapse presenting as neurolymphomatosis of the median nerve

Rebecca Tai, Julian Maingard, Mithun Nambiar, Kelvin Lim

Research output: Contribution to journalArticleOtherpeer-review

5 Citations (Scopus)

Abstract

Neurolymphomatosis (NL) is the infiltration of lymphocytes into the peripheral nervous system in a haematological malignancy. We describe the imaging features of NL in a patient with relapsed Burkitt-like non-Hodgkin's lymphoma on positron emission tomography (PET) and ultrasound. Imaging features on ultrasound are infrequently described and provide useful information in helping to establish an imaging diagnosis of NL. Features of NL in our patient included intense linear fluorodeoxyglucose-18 (18 FDG) uptake on PET along the affected median nerve. B-mode ultrasound demonstrated concentric tubular thickening and loss of fascicular architecture. Perineural and intraneural vascularity was present on colour Doppler ultrasound. It is important to be able to correlate ultrasound findings to features observed on 18 FDG-PET as this AIDS in diagnosis and in guiding potential surgical biopsy.

Original languageEnglish
Article numbere228742
Number of pages3
JournalBMJ Case Reports
Volume12
Issue number3
DOIs
Publication statusPublished - 1 Mar 2019
Externally publishedYes

Keywords

  • haematology (incl blood transfusion)
  • peripheral nerve disease
  • radiology

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