High-flow nasal cannula oxygen in acute respiratory failure after extubation: Key practical topics and clinical implications

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Traditionally, oxygen therapy has been provided by way of a range of devices such as nasal prongs, face masks, and nose masks, the design of which has changed little since the initial versions were developed more than 80 years ago. Limitations to the provision of oxygen by conventional systems exist, including patient discomfort and intolerance, inaccurate delivery of oxygen, failure to provide flow equivalent to inspiratory demand, drying of the airway, and treatment failure requiring escalation of respiratory support. Nasal high-flow oxygen therapy (NHF) has come to be used widely in the treatment of acute respiratory failure. NHF has been demonstrated to be easy to institute, is comfortable to the patient, and achieves excellent adherence to therapy [1].

Original languageEnglish
Title of host publicationNoninvasive Mechanical Ventilation and Difficult Weaning in Critical Care
Subtitle of host publicationKey Topics and Practical Approaches
EditorsAntonio M. Esquinas
Place of PublicationSwitzerland
Number of pages8
ISBN (Electronic)9783319042596
ISBN (Print)9783319042589
Publication statusPublished - 1 Jan 2016
Externally publishedYes


  • Nasal high-flow oxygen therapy
  • Respiratory failure

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