High-definition transcranial direct current stimulation in anorexia nervosa: A pilot study

Andrea Phillipou, Melissa Kirkovski, David J. Castle, Caroline Gurvich, Larry A. Abel, Stephanie Miles, Susan L. Rossell

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Objective: Anorexia nervosa (AN) is a serious psychiatric condition often associated with poor outcomes. Biologically informed treatments for AN, such as brain stimulation, are lacking, in part due to the unclear nature of the neurobiological contributions to the illness. However, recent research has suggested a specific neurobiological target for the treatment of AN, namely stimulation of the inferior parietal lobe (IPL). The aim of this study was to stimulate—noninvasively—the left IPL in individuals with AN using high-definition transcranial direct current stimulation (HD-tDCS). Method: Twenty participants will be randomized to receive 10 daily sessions of HD-tDCS or sham HD-tDCS (placebo). Assessments will be carried out at baseline and end point, as well as 4- and 12-week follow-ups. Discussion: This pilot investigation will primarily determine the feasibility and acceptability of this intervention.

Original languageEnglish
Pages (from-to)1274-1280
Number of pages7
JournalInternational Journal of Eating Disorders
Volume52
Issue number11
DOIs
Publication statusPublished - 1 Nov 2019

Keywords

  • anorexia nervosa
  • body image
  • brain stimulation
  • eating disorder
  • parietal cortex
  • tDCS

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