High bias gas flows increase lung injury in the ventilated preterm lamb

Katinka P Bach; Carl Kuschel; Stuart Brian Hooper; Jean Bertram; Sue McKnight; Shirley E Peachey; Valerie Anne Zahra; Sharon Jayne Flecknoe; Mark H Oliver; Megan Jane Wallace; Frank H Bloomfield

doi:10.1371/journal.pone.0047044

High bias gas flows increase lung injury in the ventilated preterm lamb

Katinka P Bach, Carl Kuschel, Stuart Brian Hooper, Jean Bertram, Sue McKnight, Shirley E Peachey, Valerie Anne Zahra, Sharon Jayne Flecknoe, Mark H Oliver, Megan Jane Wallace, Frank H Bloomfield

Hudson Institute - The Ritchie Centre

Research output: Contribution to journal › Article › Research › peer-review

15 Citations (Scopus)

Abstract

Mechanical ventilation of preterm babies increases survival but can also cause ventilator-induced lung injury (VILI), leading to the development of bronchopulmonary dysplasia (BPD). It is not known whether shear stress injury from gases flowing into the preterm lung during ventilation contributes to VILI.

Original language	English
Article number	e47044
Number of pages	9
Journal	PLoS ONE
Volume	7
Issue number	10
DOIs	https://doi.org/10.1371/journal.pone.0047044
Publication status	Published - 2012

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10.1371/journal.pone.0047044Licence: CC BY

2177806-oaFinal published version, 447 KBLicence: CC BY

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title = "High bias gas flows increase lung injury in the ventilated preterm lamb",

abstract = "Mechanical ventilation of preterm babies increases survival but can also cause ventilator-induced lung injury (VILI), leading to the development of bronchopulmonary dysplasia (BPD). It is not known whether shear stress injury from gases flowing into the preterm lung during ventilation contributes to VILI.",

author = "Bach, {Katinka P} and Carl Kuschel and Hooper, {Stuart Brian} and Jean Bertram and Sue McKnight and Peachey, {Shirley E} and Zahra, {Valerie Anne} and Flecknoe, {Sharon Jayne} and Oliver, {Mark H} and Wallace, {Megan Jane} and Bloomfield, {Frank H}",

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AU - Bach, Katinka P

AU - Kuschel, Carl

AU - Hooper, Stuart Brian

AU - Bertram, Jean

AU - McKnight, Sue

AU - Peachey, Shirley E

AU - Zahra, Valerie Anne

AU - Flecknoe, Sharon Jayne

AU - Oliver, Mark H

AU - Wallace, Megan Jane

AU - Bloomfield, Frank H

PY - 2012

Y1 - 2012

N2 - Mechanical ventilation of preterm babies increases survival but can also cause ventilator-induced lung injury (VILI), leading to the development of bronchopulmonary dysplasia (BPD). It is not known whether shear stress injury from gases flowing into the preterm lung during ventilation contributes to VILI.

AB - Mechanical ventilation of preterm babies increases survival but can also cause ventilator-induced lung injury (VILI), leading to the development of bronchopulmonary dysplasia (BPD). It is not known whether shear stress injury from gases flowing into the preterm lung during ventilation contributes to VILI.

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JO - PLoS ONE

JF - PLoS ONE

SN - 1932-6203

IS - 10

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ER -

High bias gas flows increase lung injury in the ventilated preterm lamb

Abstract

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