Heterogeneity of renal cortical oxygenation: seeing is believing

Roger G. Evans; Connie P.C. Ow

doi:10.1016/j.kint.2018.01.039

Heterogeneity of renal cortical oxygenation: seeing is believing

Roger G. Evans, Connie P.C. Ow

Research output: Contribution to journal › Editorial › Other › peer-review

5 Citations (Scopus)

Abstract

The limited spatial and temporal resolution of available methods for quantifying renal tissue oxygen tension is a major impediment to identification of the roles of renal hypoxia in kidney diseases. Intravital phosphorescence lifetime imaging microscopy allows cellular oxygen tension in the renal cortex of live animals to be resolved to the level of individual tubular cross-sections. This paves the way for future investigations of the spatial relationships between cellular hypoxia and pathophysiological events in kidney disease.

Original language	English
Pages (from-to)	1278-1280
Number of pages	3
Journal	Kidney International
Volume	93
Issue number	6
DOIs	https://doi.org/10.1016/j.kint.2018.01.039
Publication status	Published - 1 Jun 2018

Access to Document

10.1016/j.kint.2018.01.039

Cite this

@article{cf30b2fc27214f7b81b1d774442afd6a,

title = "Heterogeneity of renal cortical oxygenation: seeing is believing",

abstract = "The limited spatial and temporal resolution of available methods for quantifying renal tissue oxygen tension is a major impediment to identification of the roles of renal hypoxia in kidney diseases. Intravital phosphorescence lifetime imaging microscopy allows cellular oxygen tension in the renal cortex of live animals to be resolved to the level of individual tubular cross-sections. This paves the way for future investigations of the spatial relationships between cellular hypoxia and pathophysiological events in kidney disease.",

author = "Evans, {Roger G.} and Ow, {Connie P.C.}",

year = "2018",

month = jun,

day = "1",

doi = "10.1016/j.kint.2018.01.039",

language = "English",

volume = "93",

pages = "1278--1280",

journal = "Kidney International",

issn = "0085-2538",

publisher = "Elsevier",

number = "6",

}

TY - JOUR

T1 - Heterogeneity of renal cortical oxygenation

T2 - seeing is believing

AU - Evans, Roger G.

AU - Ow, Connie P.C.

PY - 2018/6/1

Y1 - 2018/6/1

N2 - The limited spatial and temporal resolution of available methods for quantifying renal tissue oxygen tension is a major impediment to identification of the roles of renal hypoxia in kidney diseases. Intravital phosphorescence lifetime imaging microscopy allows cellular oxygen tension in the renal cortex of live animals to be resolved to the level of individual tubular cross-sections. This paves the way for future investigations of the spatial relationships between cellular hypoxia and pathophysiological events in kidney disease.

AB - The limited spatial and temporal resolution of available methods for quantifying renal tissue oxygen tension is a major impediment to identification of the roles of renal hypoxia in kidney diseases. Intravital phosphorescence lifetime imaging microscopy allows cellular oxygen tension in the renal cortex of live animals to be resolved to the level of individual tubular cross-sections. This paves the way for future investigations of the spatial relationships between cellular hypoxia and pathophysiological events in kidney disease.

UR - http://www.scopus.com/inward/record.url?scp=85047008190&partnerID=8YFLogxK

U2 - 10.1016/j.kint.2018.01.039

DO - 10.1016/j.kint.2018.01.039

M3 - Editorial

AN - SCOPUS:85047008190

SN - 0085-2538

VL - 93

SP - 1278

EP - 1280

JO - Kidney International

JF - Kidney International

IS - 6

ER -

Heterogeneity of renal cortical oxygenation: seeing is believing

Abstract

Access to Document

Other files and links

Cite this