Heparin-induced thrombocytopenia and the use of r-hirudin during cardiopulmonary bypass

S. Manikappa; K. Benfield; T. E. Gan; J. Butler; E. Malan; H. A.M. Tran; A. Tucker

doi:10.1177/0310057x0503300316

Heparin-induced thrombocytopenia and the use of r-hirudin during cardiopulmonary bypass

S. Manikappa, K. Benfield, T. E. Gan, J. Butler, E. Malan, H. A.M. Tran, A. Tucker

Research output: Contribution to journal › Article › Research › peer-review

4 Citations (Scopus)

Abstract

We report the successful use of r-hirudin (lepirudin) for cardiopulmonary bypass in a 67-year-old man who developed heparin-induced thrombocytopenia type II during heparin treatment of an extensive deep venous thrombosis. Lepirudin was monitored by the modified ecarin clotting time in a "mobile laboratory" set up next to the cardiac theatre, aiming for lepirudin levels of 3.5 to 4.5 μl/ml during bypass.

Original language	English
Pages (from-to)	388-392
Number of pages	5
Journal	Anaesthesia and Intensive Care
Volume	33
Issue number	3
DOIs	https://doi.org/10.1177/0310057x0503300316
Publication status	Published - Jun 2005
Externally published	Yes

Keywords

R-hirudin
Thrombocytopena: heparin-induced, cardiopulmonary bypass

Access to Document

10.1177/0310057x0503300316

Link to publication in Scopus

Cite this

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title = "Heparin-induced thrombocytopenia and the use of r-hirudin during cardiopulmonary bypass",

abstract = "We report the successful use of r-hirudin (lepirudin) for cardiopulmonary bypass in a 67-year-old man who developed heparin-induced thrombocytopenia type II during heparin treatment of an extensive deep venous thrombosis. Lepirudin was monitored by the modified ecarin clotting time in a {"}mobile laboratory{"} set up next to the cardiac theatre, aiming for lepirudin levels of 3.5 to 4.5 μl/ml during bypass.",

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AU - Manikappa, S.

AU - Benfield, K.

AU - Gan, T. E.

AU - Butler, J.

AU - Malan, E.

AU - Tran, H. A.M.

AU - Tucker, A.

PY - 2005/6

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AB - We report the successful use of r-hirudin (lepirudin) for cardiopulmonary bypass in a 67-year-old man who developed heparin-induced thrombocytopenia type II during heparin treatment of an extensive deep venous thrombosis. Lepirudin was monitored by the modified ecarin clotting time in a "mobile laboratory" set up next to the cardiac theatre, aiming for lepirudin levels of 3.5 to 4.5 μl/ml during bypass.

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KW - Thrombocytopena: heparin-induced, cardiopulmonary bypass

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