Hemorrhage induces c-fos immunoreactivity in spinally projecting neurons of cat subretrofacial nucleus

R. M. McAllen; E. Badoer; A. D. Shafton; B. J. Oldfield; M. J. McKinley

doi:10.1016/0006-8993(92)90099-U

Hemorrhage induces c-fos immunoreactivity in spinally projecting neurons of cat subretrofacial nucleus

R. M. McAllen, E. Badoer, A. D. Shafton, B. J. Oldfield, M. J. McKinley

Research output: Contribution to journal › Article › Research › peer-review

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Abstract

Neuronal expression of c-fos product in the cat rostral ventrolateral medulla was studied by immunohistochemistry. Spinally projecting neurons of the subretrofacial (SRF) nucleus were pre-labeled by retrograde transport of fluorescent latex microspheres from the lumbar cord. In 3 animals which were bled by approximately 25% blood volume from a carotid cannula, 48-62% of SRF-spinal neurons expressed c-fos immunoreactivity. In 2 control animals, the corresponding values were 2% and 4%. The data show that bulbospinal neurons of presumed vasomotor function express c-fos in response to hemorrhage.

Original language	English
Pages (from-to)	329-332
Number of pages	4
Journal	Brain Research
Volume	575
Issue number	2
DOIs	https://doi.org/10.1016/0006-8993(92)90099-U
Publication status	Published - 20 Mar 1992
Externally published	Yes

Keywords

Blood pressure
C-fos
Hemorrhage
Vasomotor pathway
Ventrolateral medulla

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10.1016/0006-8993(92)90099-U

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title = "Hemorrhage induces c-fos immunoreactivity in spinally projecting neurons of cat subretrofacial nucleus",

abstract = "Neuronal expression of c-fos product in the cat rostral ventrolateral medulla was studied by immunohistochemistry. Spinally projecting neurons of the subretrofacial (SRF) nucleus were pre-labeled by retrograde transport of fluorescent latex microspheres from the lumbar cord. In 3 animals which were bled by approximately 25% blood volume from a carotid cannula, 48-62% of SRF-spinal neurons expressed c-fos immunoreactivity. In 2 control animals, the corresponding values were 2% and 4%. The data show that bulbospinal neurons of presumed vasomotor function express c-fos in response to hemorrhage.",

keywords = "Blood pressure, C-fos, Hemorrhage, Vasomotor pathway, Ventrolateral medulla",

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T1 - Hemorrhage induces c-fos immunoreactivity in spinally projecting neurons of cat subretrofacial nucleus

AU - McAllen, R. M.

AU - Badoer, E.

AU - Shafton, A. D.

AU - Oldfield, B. J.

AU - McKinley, M. J.

PY - 1992/3/20

Y1 - 1992/3/20

N2 - Neuronal expression of c-fos product in the cat rostral ventrolateral medulla was studied by immunohistochemistry. Spinally projecting neurons of the subretrofacial (SRF) nucleus were pre-labeled by retrograde transport of fluorescent latex microspheres from the lumbar cord. In 3 animals which were bled by approximately 25% blood volume from a carotid cannula, 48-62% of SRF-spinal neurons expressed c-fos immunoreactivity. In 2 control animals, the corresponding values were 2% and 4%. The data show that bulbospinal neurons of presumed vasomotor function express c-fos in response to hemorrhage.

AB - Neuronal expression of c-fos product in the cat rostral ventrolateral medulla was studied by immunohistochemistry. Spinally projecting neurons of the subretrofacial (SRF) nucleus were pre-labeled by retrograde transport of fluorescent latex microspheres from the lumbar cord. In 3 animals which were bled by approximately 25% blood volume from a carotid cannula, 48-62% of SRF-spinal neurons expressed c-fos immunoreactivity. In 2 control animals, the corresponding values were 2% and 4%. The data show that bulbospinal neurons of presumed vasomotor function express c-fos in response to hemorrhage.

KW - Blood pressure

KW - C-fos

KW - Hemorrhage

KW - Vasomotor pathway

KW - Ventrolateral medulla

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DO - 10.1016/0006-8993(92)90099-U

M3 - Article

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AN - SCOPUS:0026587745

SN - 0006-8993

VL - 575

SP - 329

EP - 332

JO - Brain Research

JF - Brain Research

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ER -

Hemorrhage induces c-fos immunoreactivity in spinally projecting neurons of cat subretrofacial nucleus

Abstract

Keywords

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