Hemodynamic evaluation of normally functioning sulzer carbomedics prosthetic valves

Nurgül Keser, Navin C. Nanda, Andrew P. Miller, Szilard Voros, Cahide Soydas, Gopal Agrawal, Chiara Liguori, David Naftel, Albert D. Pacifico, James K. Kirklin, David C. McGiffin, William L. Holman

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The Sulzer Carbomedics prosthetic heart valve (CP) is a commonly used mechanical valve in clinical practice. In the present study, we used conventional and color Doppler echocardiography to assess the hemodynamics of normally functioning CP in the aortic (n = 73) and mitral (n = 127) positions. Our findings demonstrate no significant correlation of Doppler-measured peak and mean pressure gradients and effective orifice area with implanted valve size and actual orifice areas, measured directly by the manufacturer for CPs in both the mitral and aortic positions. However, it is still useful to measure effective orifice area by Doppler because a value in the normal or nonstenotic range points to an unobstructed prosthesis in the aortic or mitral position, in the absence of poor left ventricular ejection fraction. A value in the stenotic range could mean a normally functioning or obstructed prosthesis and, therefore, may need further investigation, such as assessment of valve leaflet motion by transthoracic or transesophageal echocardiography or fluoroscopy. Valve regurgitation as evaluated by color Doppler flow mapping was mild in practically all CPs in the aortic position, and in the majority of CPs in the mitral position.

Original languageEnglish
Pages (from-to)649-657
Number of pages9
JournalUltrasound in Medicine and Biology
Issue number5
Publication statusPublished - 1 May 2003
Externally publishedYes


  • Echocardiography
  • Prosthetic heart valve
  • Sulzer Carbomedics prosthetic heart valve

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