The hedgehog (hh) gene family encode secreted proteins that are involved in a number of developmental processes in vertebrates and invertebrates. These include the patterning of the vertebrate neural tube, somites, limb and brain and the Drosophila embryonic epidermis and larval imaginal discs. Hh proteins show a high degree of sequence identity within and between species. Recent analysis has demonstrated that this family of molecules may act in a mechanistically similar way to provide positional signalling within different phyla.
|Number of pages||18|
|Journal||Netherlands Journal of Zoology|
|Publication status||Published - Jul 1996|