Projects per year
Abstract
Objective: To evaluate the impact of an integrated diabetes and kidney disease model of care on health-related quality of life (HRQOL) of patients with comorbid diabetes and chronic kidney disease (CKD). Research design and methods: A longitudinal study of adult patients (over 18 years) with comorbid diabetes and CKD (stage 3a or worse) who attended a new diabetes kidney disease service was conducted at a tertiary hospital. A questionnaire consisting of demographics, clinical data, and the Kidney Disease Quality of Life (KDQOL-36) was administered at baseline and after 12 months. Paired t-tests were used to compare baseline and 12-month scores. A subgroup analysis examined the effects by patient gender. Multiple regression analysis examined the factors associated with changes in scores. Results: 179 patients, 36% of whom were female, with baseline mean±SD age of 65.9±11.3 years, were studied. Across all subscales, HRQOL did not significantly change over time (p value for all mean differences >0.05). However, on subgroup analysis, symptom problem list and physical composite summary scores increased among women (MD=9.0, 95% CI 1.25 to 16.67; p=0.02 and MD=4.5, 95% CI 0.57 to 8.42; p=0.03 respectively) and physical composite scores decreased among men (MD=-3.35, 95% CI -6.26 to -0.44; p=0.03). Conclusion The HRQOL of patients with comorbid diabetes and CKD attending a new codesigned, integrated diabetes and kidney disease model of care was maintained over 12 months. Given that HRQOL is known to deteriorate over time in this high-risk population, the impact of these findings on clinical outcomes warrants further investigation.
Original language | English |
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Article number | e000842 |
Number of pages | 8 |
Journal | BMJ Open Diabetes Research & Care |
Volume | 8 |
Issue number | 1 |
DOIs | |
Publication status | Published - 6 Jan 2020 |
Keywords
- chronic kidney disease
- quality of Life
- type 2 diabetes
Projects
- 3 Finished
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NHMRC Research Fellowship
National Health and Medical Research Council (NHMRC) (Australia)
1/01/15 → 31/12/19
Project: Research
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NHMRC Practitioner Fellowship
National Health and Medical Research Council (NHMRC) (Australia)
1/01/13 → 31/12/17
Project: Research
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The Diabetes Renal Project: Better Outcomes for Patients with Diabetes and Chronic Kidney Disease
Zoungas, S., Teede, H., Kerr, P., Cass, A., Gallagher, M. P., Fulcher, G. R., Walker, R., Polkinghorne, K., Russell, G. & Johnson, G.
National Health and Medical Research Council (NHMRC) (Australia), George Institute for Global Health (Australia)
1/10/12 → 30/09/16
Project: Research