TY - JOUR
T1 - Have outcomes following extremely preterm birth improved over time?
AU - Cheong, Jeanie LY
AU - Spittle, Alicia J.
AU - Burnett, Alice C.
AU - Anderson, Peter J.
AU - Doyle, Lex W.
PY - 2020/5/15
Y1 - 2020/5/15
N2 - Increased survival of infants born preterm, especially those born extremely preterm (<28 weeks’ gestation), has meant that more are reaching later childhood and adulthood. As preterm birth is associated with a higher risk of neurodevelopmental deficits, the aim of this review was to determine whether or not the advances in perinatal care that led to improved survival have also had a positive impact on long-term neurodevelopment. Studies examining temporal changes in neurodevelopment are limited, and only from high-income countries. However, based on available published data, there is no definite trend of improved neurodevelopment at school age for neurosensory, cognitive, academic achievement, motor or executive function with time. Cerebral palsy rates, however, may be decreasing. More research is needed into the potential contributors for the trends observed, and also for other outcomes such as mental health and behavior.
AB - Increased survival of infants born preterm, especially those born extremely preterm (<28 weeks’ gestation), has meant that more are reaching later childhood and adulthood. As preterm birth is associated with a higher risk of neurodevelopmental deficits, the aim of this review was to determine whether or not the advances in perinatal care that led to improved survival have also had a positive impact on long-term neurodevelopment. Studies examining temporal changes in neurodevelopment are limited, and only from high-income countries. However, based on available published data, there is no definite trend of improved neurodevelopment at school age for neurosensory, cognitive, academic achievement, motor or executive function with time. Cerebral palsy rates, however, may be decreasing. More research is needed into the potential contributors for the trends observed, and also for other outcomes such as mental health and behavior.
KW - Academic function
KW - Cerebral palsy
KW - Cognitive function
KW - Extremely low birthweight
KW - Extremely preterm
KW - Motor impairment
UR - http://www.scopus.com/inward/record.url?scp=85085041493&partnerID=8YFLogxK
U2 - 10.1016/j.siny.2020.101114
DO - 10.1016/j.siny.2020.101114
M3 - Article
AN - SCOPUS:85085041493
JO - Seminars in Fetal and Neonatal Medicine
JF - Seminars in Fetal and Neonatal Medicine
SN - 1744-165X
M1 - 101114
ER -