Harmonised Australian Reference Intervals for Serum PINP and CTX in Adults

Samuel D Vasikaran; S A Paul Chubb; Peter R Ebeling; Nicole Jenkins; Graham R D Jones; Mark A Kotowicz; Howard A Morris; Hans-Gerhard Schneider; Markus J Seibel; Greg Ward

Harmonised Australian Reference Intervals for Serum PINP and CTX in Adults

Samuel D Vasikaran, S A Paul Chubb, Peter R Ebeling, Nicole Jenkins, Graham R D Jones, Mark A Kotowicz, Howard A Morris, Hans-Gerhard Schneider, Markus J Seibel, Greg Ward

Research output: Contribution to journal › Review Article › Other › peer-review

Abstract

Bone turnover markers (BTMs) are classified as either formation or resorption markers. Their concentrations in blood or urine of adults are considered to reflect the rate of bone remodelling and may be of use in the management of patients with bone disease. Major inter-method differences exist for BTMs, and harmonisation of methods is currently being pursued at an international level. Based on published data, this article describes age- and sex-specific Australian consensus reference intervals for adults for serum procollagen type I amino-terminal propeptide (s-PINP) and serum β-isomerised carboxy-terminal cross-linking telopeptide of type I collagen (s-CTX).

Original language	English
Pages (from-to)	237-242
Number of pages	6
Journal	Clinical Biochemist Reviews
Volume	35
Issue number	4
Publication status	Published - 2014

Cite this

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title = "Harmonised Australian Reference Intervals for Serum PINP and CTX in Adults",

abstract = "Bone turnover markers (BTMs) are classified as either formation or resorption markers. Their concentrations in blood or urine of adults are considered to reflect the rate of bone remodelling and may be of use in the management of patients with bone disease. Major inter-method differences exist for BTMs, and harmonisation of methods is currently being pursued at an international level. Based on published data, this article describes age- and sex-specific Australian consensus reference intervals for adults for serum procollagen type I amino-terminal propeptide (s-PINP) and serum β-isomerised carboxy-terminal cross-linking telopeptide of type I collagen (s-CTX).",

author = "Vasikaran, {Samuel D} and Chubb, {S A Paul} and Ebeling, {Peter R} and Nicole Jenkins and Jones, {Graham R D} and Kotowicz, {Mark A} and Morris, {Howard A} and Hans-Gerhard Schneider and Seibel, {Markus J} and Greg Ward",

year = "2014",

language = "English",

volume = "35",

pages = "237--242",

journal = "Clinical Biochemist Reviews",

issn = "0159-8090",

publisher = "Australasian Association for Clinical Biochemistry and Laboratory Medicine (AACB)",

number = "4",

}

TY - JOUR

T1 - Harmonised Australian Reference Intervals for Serum PINP and CTX in Adults

AU - Vasikaran, Samuel D

AU - Chubb, S A Paul

AU - Ebeling, Peter R

AU - Jenkins, Nicole

AU - Jones, Graham R D

AU - Kotowicz, Mark A

AU - Morris, Howard A

AU - Schneider, Hans-Gerhard

AU - Seibel, Markus J

AU - Ward, Greg

PY - 2014

Y1 - 2014

N2 - Bone turnover markers (BTMs) are classified as either formation or resorption markers. Their concentrations in blood or urine of adults are considered to reflect the rate of bone remodelling and may be of use in the management of patients with bone disease. Major inter-method differences exist for BTMs, and harmonisation of methods is currently being pursued at an international level. Based on published data, this article describes age- and sex-specific Australian consensus reference intervals for adults for serum procollagen type I amino-terminal propeptide (s-PINP) and serum β-isomerised carboxy-terminal cross-linking telopeptide of type I collagen (s-CTX).

AB - Bone turnover markers (BTMs) are classified as either formation or resorption markers. Their concentrations in blood or urine of adults are considered to reflect the rate of bone remodelling and may be of use in the management of patients with bone disease. Major inter-method differences exist for BTMs, and harmonisation of methods is currently being pursued at an international level. Based on published data, this article describes age- and sex-specific Australian consensus reference intervals for adults for serum procollagen type I amino-terminal propeptide (s-PINP) and serum β-isomerised carboxy-terminal cross-linking telopeptide of type I collagen (s-CTX).

M3 - Review Article

SN - 0159-8090

VL - 35

SP - 237

EP - 242

JO - Clinical Biochemist Reviews

JF - Clinical Biochemist Reviews

IS - 4

ER -