Hand amyotrophy and ventral intraspinal fluid collection

Painless progressive amyotrophy of the hands is highly suggestive of amyotrophic lateral sclerosis (ALS) or its variants and imaging of the cervical spinal cord constitutes part of the work-up that follows. Recently, ventral longitudinal intraspinal fluid-filled collections (VLISFC) have been described as a potentially treatable cause of brachial amyotrophy (1-3). Here we describe a new case with progressive and painless hand weakness and describe the clinical and typical neuroimaging findings to highlight this disorder in the differential diagnosis of upper limb amyotrophy