Hampered by historical paradigms--echinocandins and the treatment of Candida endocarditis

Bradley J Gardiner; Monica Anne Slavin; Tony Korman; Rhonda Lee Stuart

doi:10.1111/myc.12154

Hampered by historical paradigms--echinocandins and the treatment of Candida endocarditis

Medicine Monash Health

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7 Citations (Scopus)

Abstract

Infective endocarditis due to Candida sp. has a high mortality rate. Traditionally, management involves early surgery and prolonged amphotericin +/- flucytosine. We report a case of Candida parapsilosis bileaflet mitral valve endocarditis cured with anidulafungin and fluconazole, and review the role of echinocandins in the management of Candida endocarditis.

Original language	English
Pages (from-to)	316-319
Number of pages	4
Journal	Mycoses
Volume	57
Issue number	5
DOIs	https://doi.org/10.1111/myc.12154
Publication status	Published - 2014

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10.1111/myc.12154

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title = "Hampered by historical paradigms--echinocandins and the treatment of Candida endocarditis",

abstract = "Infective endocarditis due to Candida sp. has a high mortality rate. Traditionally, management involves early surgery and prolonged amphotericin +/- flucytosine. We report a case of Candida parapsilosis bileaflet mitral valve endocarditis cured with anidulafungin and fluconazole, and review the role of echinocandins in the management of Candida endocarditis.",

author = "Gardiner, \{Bradley J\} and Slavin, \{Monica Anne\} and Tony Korman and Stuart, \{Rhonda Lee\}",

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AU - Gardiner, Bradley J

AU - Slavin, Monica Anne

AU - Korman, Tony

AU - Stuart, Rhonda Lee

PY - 2014

Y1 - 2014

N2 - Infective endocarditis due to Candida sp. has a high mortality rate. Traditionally, management involves early surgery and prolonged amphotericin +/- flucytosine. We report a case of Candida parapsilosis bileaflet mitral valve endocarditis cured with anidulafungin and fluconazole, and review the role of echinocandins in the management of Candida endocarditis.

AB - Infective endocarditis due to Candida sp. has a high mortality rate. Traditionally, management involves early surgery and prolonged amphotericin +/- flucytosine. We report a case of Candida parapsilosis bileaflet mitral valve endocarditis cured with anidulafungin and fluconazole, and review the role of echinocandins in the management of Candida endocarditis.

UR - http://www.ncbi.nlm.nih.gov/pubmed/24251958

U2 - 10.1111/myc.12154

DO - 10.1111/myc.12154

M3 - Article

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VL - 57

SP - 316

EP - 319

JO - Mycoses

JF - Mycoses

IS - 5

ER -

Hampered by historical paradigms--echinocandins and the treatment of Candida endocarditis

Abstract

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