H-4 histamine receptor

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The human histamine H 4 receptor was only recently cloned (in late 2000). As a result, very little is known about its function. It has approximately 40% amino acid sequence homology with the human histamine H 3 receptor, and this increases to 60% when comparing only the transmembrane regions. It couples to G i to inhibit cyclic AMP accumulation.

Original languageEnglish
Title of host publicationxPharm
Subtitle of host publicationThe Comprehensive Pharmacology Reference
PublisherAcademic Press
Number of pages7
ISBN (Print)9780080552323
Publication statusPublished - 2011
Externally publishedYes

Cite this

Powell, K. (2011). H-4 histamine receptor. In xPharm: The Comprehensive Pharmacology Reference (pp. 1-7). Academic Press. https://doi.org/10.1016/B978-008055232-3.60121-7