H-2 histamine receptor

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Abstract

The histamine H 2 receptor gene has been cloned from human, rat, mouse, dog and guinea pig. The receptor is present in gastric parietal cells, vascular smooth muscle and neutrophils as well as in the central nervous system. H 2 receptor antagonists have been used for many years clinically for the treatment of peptic ulcers in the gastrointestinal tract and are among the most widely prescribed drugs across the western world.

Original languageEnglish
Title of host publicationxPharm
Subtitle of host publicationThe Comprehensive Pharmacology Reference
PublisherAcademic Press
Pages1-6
Number of pages6
ISBN (Print)9780080552323
DOIs
Publication statusPublished - 2011
Externally publishedYes

Cite this

Powell, K. (2011). H-2 histamine receptor. In xPharm: The Comprehensive Pharmacology Reference (pp. 1-6). Academic Press. https://doi.org/10.1016/B978-008055232-3.60119-9