Guidelines for the prevention of sepsis in asplenic and hyposplenic patients

D. Spelman, J. Buttery, A. Daley, D. Isaacs, I. Jennens, A. Kakakios, R. Lawrence, S. Roberts, A. Torda, D. A R Watson, I. Woolley, T. Anderson, A. Street

Research output: Contribution to journalReview ArticleResearchpeer-review

59 Citations (Scopus)

Abstract

Asplenic or hyposplenic patients are at risk of fulminant sepsis. This entity has a mortality of up to 50%. The spectrum of causative organisms is evolving as are recommended preventive strategies, which include education, prophylactic and standby antibiotics, preventive immunizations, optimal antimalarial advice when visiting endemic countries and early management of animal bites. However, there is evidence that adherence to these strategies is poor. Consensus-updated guidelines have been developed to help Australian and New Zealand clinicians and patients in the prevention of sepsis in asplenic and hyposplenic patients.

Original languageEnglish
Pages (from-to)349-356
Number of pages8
JournalInternal Medicine Journal
Volume38
Issue number5
DOIs
Publication statusPublished - May 2008

Keywords

  • Antibiotics
  • Asplenia
  • Hyposplenia
  • Immunization
  • Spleen

Cite this