Guideline on premature ovarian insufficiency

Nick Panay; Richard A.A. Anderson; Amy Bennie; Marcelle Cedars; Melanie J Davies; Carolyn Ee; Claus H. Gravholt; Sophia Kalantaridou; Amanda Kallen; Kimberly Q. Kim; Micheline Misrahi; Aya Mousa; Rossella E. Nappi; Walter A. Rocca; Xiangyan Ruan; Helena J. Teede; Nathalie Vermeulen; Elinor Vogt; Amanda J. Vincent

Guideline on premature ovarian insufficiency

Nick Panay, Richard A.A. Anderson, Amy Bennie, Marcelle Cedars, Melanie J Davies, Carolyn Ee, Claus H. Gravholt, Sophia Kalantaridou, Amanda Kallen, Kimberly Q. Kim, Micheline Misrahi, Aya Mousa, Rossella E. Nappi, Walter A. Rocca, Xiangyan Ruan, Helena J. Teede, Nathalie Vermeulen, Elinor Vogt, Amanda J. Vincent

Monash Centre for Health Research & Implementation

Research output: Book/Report › Other Report › Other

Abstract

This updated guideline offers best practice recommendations for the care of women with with both primary and secondary premature ovarian insufficiency (POI). POI is a clinical condition defined by the loss of ovarian function indicated by irregular menstrual cycles together with biochemical confirmation of ovarian insufficiency before the age of 40.

Women with POI have unique needs. They may not only suffer from symptoms associated with estrogen deficiency, but can also experience other issues, with a significant impact on their quality of life and later health outcomes. POI can have significant effects on fertility, bone health, cardiovascular health, sexual function, psychological health and neurological function.

The impact of POI on these different domains and the treatment options for each along with monitoring needs where relevant are all discussed in the guideline.

In addition to hormone therapy the guideline also covers non-hormonal and complementary treatments, lifestyle interventions and puberty induction.

This guideline is an updated version and replaces the ESHRE Guideline on the management of women with POI (2016) (see https://doi.org/10.1093/humrep/dew027)

Original language	English
Publisher	European Society of Human Reproduction and Embryology (ESHRE)
Publication status	Published - 2024

Access to Document

https://www.eshre.eu/Guidelines-and-Legal/Guidelines/Premature-ovarian-insufficiency

3 Article

Evidence-based guideline: Premature Ovarian Insufficiency
Panay, N., Anderson, R. A. A., Bennie, A., Cedars, M., Davies, M. J., Ee, C., Gravholt, C. H., Kalantaridou, S., Kallen, A., Kim, K. Q., Misrahi, M., Mousa, A., Nappi, R. E., Rocca, W. A., Ruan, X., Teede, H. J., Vermeulen, N., Vogt, E., Vincent, A. J. & ESHRE, ASRM, CREWHIRL and IMS Guideline Group on POI, Feb 2025, In: Fertility and Sterility. 123, 2, p. 221-236 17 p.
Research output: Contribution to journal › Article › Other › peer-review

Open Access

3 Citations (Scopus)
Evidence-based guideline: premature ovarian insufficiency^†‡
Panay, N., Anderson, R. A., Bennie, A., Cedars, M., Davies, M., Ee, C., Gravholt, C. H., Kalantaridou, S., Kallen, A., Kim, K. Q., Misrahi, M., Mousa, A., Nappi, R. E., Rocca, W. A., Ruan, X., Teede, H., Vermeulen, N., Vogt, E., Vincent, A. J. & ESHRE, ASRM, CREWHIRL and IMS Guideline Group on POI, 2024, In: Human Reproduction Open. 2024, 4, 14 p., hoae065.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

9 Citations (Scopus)
Evidence-based guideline: premature ovarian insufficiency^†^‡
Panay, N., Anderson, R. A., Bennie, A., Cedars, M., Davies, M., Ee, C., Gravholt, C. H., Kalantaridou, S., Kallen, A., Kim, K. Q., Misrahi, M., Mousa, A., Nappi, R. E., Rocca, W. A., Ruan, X., Teede, H., Vermeulen, N., Vogt, E., Vincent, A. J. & ESHRE, ASRM, CREWHIRL and IMS Guideline Group on POI, 2024, In: Climacteric. 27, 6, p. 510-520 11 p.
Research output: Contribution to journal › Article › Other › peer-review

Open Access

3 Citations (Scopus)

Cite this

Panay, N., Anderson, R. A. A., Bennie, A., Cedars, M., Davies, M. J., Ee, C., Gravholt, C. H., Kalantaridou, S., Kallen, A., Kim, K. Q., Misrahi, M., Mousa, A., Nappi, R. E., Rocca, W. A., Ruan, X., Teede, H. J., Vermeulen, N., Vogt, E., & Vincent, A. J. (2024). Guideline on premature ovarian insufficiency. European Society of Human Reproduction and Embryology (ESHRE). https://www.eshre.eu/Guidelines-and-Legal/Guidelines/Premature-ovarian-insufficiency

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title = "Guideline on premature ovarian insufficiency",

abstract = "This updated guideline offers best practice recommendations for the care of women with with both primary and secondary premature ovarian insufficiency (POI). POI is a clinical condition defined by the loss of ovarian function indicated by irregular menstrual cycles together with biochemical confirmation of ovarian insufficiency before the age of 40.Women with POI have unique needs. They may not only suffer from symptoms associated with estrogen deficiency, but can also experience other issues, with a significant impact on their quality of life and later health outcomes. POI can have significant effects on fertility, bone health, cardiovascular health, sexual function, psychological health and neurological function.The impact of POI on these different domains and the treatment options for each along with monitoring needs where relevant are all discussed in the guideline.In addition to hormone therapy the guideline also covers non-hormonal and complementary treatments, lifestyle interventions and puberty induction.This guideline is an updated version and replaces the ESHRE Guideline on the management of women with POI (2016) (see https://doi.org/10.1093/humrep/dew027)",

author = "Nick Panay and Anderson, {Richard A.A.} and Amy Bennie and Marcelle Cedars and Davies, {Melanie J} and Carolyn Ee and Gravholt, {Claus H.} and Sophia Kalantaridou and Amanda Kallen and Kim, {Kimberly Q.} and Micheline Misrahi and Aya Mousa and Nappi, {Rossella E.} and Rocca, {Walter A.} and Xiangyan Ruan and Teede, {Helena J.} and Nathalie Vermeulen and Elinor Vogt and Vincent, {Amanda J.}",

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publisher = "European Society of Human Reproduction and Embryology (ESHRE)",

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Panay, N, Anderson, RAA, Bennie, A, Cedars, M, Davies, MJ, Ee, C, Gravholt, CH, Kalantaridou, S, Kallen, A, Kim, KQ, Misrahi, M, Mousa, A, Nappi, RE, Rocca, WA, Ruan, X, Teede, HJ, Vermeulen, N, Vogt, E & Vincent, AJ 2024, Guideline on premature ovarian insufficiency. European Society of Human Reproduction and Embryology (ESHRE). <https://www.eshre.eu/Guidelines-and-Legal/Guidelines/Premature-ovarian-insufficiency>

TY - BOOK

T1 - Guideline on premature ovarian insufficiency

AU - Panay, Nick

AU - Anderson, Richard A.A.

AU - Bennie, Amy

AU - Cedars, Marcelle

AU - Davies, Melanie J

AU - Ee, Carolyn

AU - Gravholt, Claus H.

AU - Kalantaridou, Sophia

AU - Kallen, Amanda

AU - Kim, Kimberly Q.

AU - Misrahi, Micheline

AU - Mousa, Aya

AU - Nappi, Rossella E.

AU - Rocca, Walter A.

AU - Ruan, Xiangyan

AU - Teede, Helena J.

AU - Vermeulen, Nathalie

AU - Vogt, Elinor

AU - Vincent, Amanda J.

PY - 2024

Y1 - 2024

N2 - This updated guideline offers best practice recommendations for the care of women with with both primary and secondary premature ovarian insufficiency (POI). POI is a clinical condition defined by the loss of ovarian function indicated by irregular menstrual cycles together with biochemical confirmation of ovarian insufficiency before the age of 40.Women with POI have unique needs. They may not only suffer from symptoms associated with estrogen deficiency, but can also experience other issues, with a significant impact on their quality of life and later health outcomes. POI can have significant effects on fertility, bone health, cardiovascular health, sexual function, psychological health and neurological function.The impact of POI on these different domains and the treatment options for each along with monitoring needs where relevant are all discussed in the guideline.In addition to hormone therapy the guideline also covers non-hormonal and complementary treatments, lifestyle interventions and puberty induction.This guideline is an updated version and replaces the ESHRE Guideline on the management of women with POI (2016) (see https://doi.org/10.1093/humrep/dew027)

AB - This updated guideline offers best practice recommendations for the care of women with with both primary and secondary premature ovarian insufficiency (POI). POI is a clinical condition defined by the loss of ovarian function indicated by irregular menstrual cycles together with biochemical confirmation of ovarian insufficiency before the age of 40.Women with POI have unique needs. They may not only suffer from symptoms associated with estrogen deficiency, but can also experience other issues, with a significant impact on their quality of life and later health outcomes. POI can have significant effects on fertility, bone health, cardiovascular health, sexual function, psychological health and neurological function.The impact of POI on these different domains and the treatment options for each along with monitoring needs where relevant are all discussed in the guideline.In addition to hormone therapy the guideline also covers non-hormonal and complementary treatments, lifestyle interventions and puberty induction.This guideline is an updated version and replaces the ESHRE Guideline on the management of women with POI (2016) (see https://doi.org/10.1093/humrep/dew027)

M3 - Other Report

BT - Guideline on premature ovarian insufficiency

PB - European Society of Human Reproduction and Embryology (ESHRE)

ER -

Guideline on premature ovarian insufficiency

Abstract

Access to Document

Research output

Evidence-based guideline: Premature Ovarian Insufficiency

Evidence-based guideline: premature ovarian insufficiency†‡

Evidence-based guideline: premature ovarian insufficiency†‡

Cite this

Evidence-based guideline: premature ovarian insufficiency^†‡

Evidence-based guideline: premature ovarian insufficiency^†^‡