Gray matter textural heterogeneity as a potential in-vivo biomarker of fine structural abnormalities in Asperger syndrome

Eugenia Radulescu; Balaji Ganeshan; Ludovico Minati; Felix D Beacher; Marcus Gray; Chris Reginald C Chatwin; Rupert C D Young; Neil Harrison; Hugo D Critchley

doi:10.1038/tpj.2012.3

Gray matter textural heterogeneity as a potential in-vivo biomarker of fine structural abnormalities in Asperger syndrome

Eugenia Radulescu, Balaji Ganeshan, Ludovico Minati, Felix D Beacher, Marcus Gray, Chris Reginald C Chatwin, Rupert C D Young, Neil Harrison, Hugo D Critchley

School of Psychological Sciences

Research output: Contribution to journal › Article › Research › peer-review

14 Citations (Scopus)

Abstract

Brain imaging studies contribute to the neurobiological understanding of Autism Spectrum Conditions (ASC). Herein, we tested the prediction that distributed neurodevelopmental abnormalities in brain development impact on the homogeneity of brain tissue measured using texture analysis (TA; a morphological method for surface pattern characterization). TA was applied to structural magnetic resonance brain scans of 54 adult participants (24 with Asperger syndrome (AS) and 30 controls).

Original language	English
Pages (from-to)	70 - 79
Number of pages	10
Journal	The Pharmacogenomics Journal
Volume	13
Issue number	1
DOIs	https://doi.org/10.1038/tpj.2012.3
Publication status	Published - 2013

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10.1038/tpj.2012.3

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Radulescu, Eugenia ; Ganeshan, Balaji ; Minati, Ludovico ; Beacher, Felix D ; Gray, Marcus ; Chatwin, Chris Reginald C ; Young, Rupert C D ; Harrison, Neil ; Critchley, Hugo D. / Gray matter textural heterogeneity as a potential in-vivo biomarker of fine structural abnormalities in Asperger syndrome. In: The Pharmacogenomics Journal. 2013 ; Vol. 13, No. 1. pp. 70 - 79.

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Gray matter textural heterogeneity as a potential in-vivo biomarker of fine structural abnormalities in Asperger syndrome. / Radulescu, Eugenia; Ganeshan, Balaji; Minati, Ludovico; Beacher, Felix D; Gray, Marcus; Chatwin, Chris Reginald C; Young, Rupert C D; Harrison, Neil; Critchley, Hugo D.

In: The Pharmacogenomics Journal, Vol. 13, No. 1, 2013, p. 70 - 79.

Research output: Contribution to journal › Article › Research › peer-review

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AU - Chatwin, Chris Reginald C

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