Gray matter textural heterogeneity as a potential in-vivo biomarker of fine structural abnormalities in Asperger syndrome

Eugenia Radulescu, Balaji Ganeshan, Ludovico Minati, Felix D Beacher, Marcus Gray, Chris Reginald C Chatwin, Rupert C D Young, Neil Harrison, Hugo D Critchley

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Abstract

Brain imaging studies contribute to the neurobiological understanding of Autism Spectrum Conditions (ASC). Herein, we tested the prediction that distributed neurodevelopmental abnormalities in brain development impact on the homogeneity of brain tissue measured using texture analysis (TA; a morphological method for surface pattern characterization). TA was applied to structural magnetic resonance brain scans of 54 adult participants (24 with Asperger syndrome (AS) and 30 controls).
Original languageEnglish
Pages (from-to)70 - 79
Number of pages10
JournalThe Pharmacogenomics Journal
Volume13
Issue number1
DOIs
Publication statusPublished - 2013

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