Granulocyte-Colony Stimulating Factor (G-CSF) as an adjunct to antibiotics in the treatment of pneumonia in adults

Allen Cheng, Dianne Stephens, Bart Currie

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Abstract

Granulocyte colony stimulating factor (G-CSF) is a naturally-occurring cytokine that has been shown to increase neutrophil function and number. Exogenous administration of recombinant G-CSF (filgrastim, pegfilgrastim or lenograstim) has found extensive use in the treatment of febrile neutropenia, but its role in the treatment of infection in non-neutropenic hosts is less well defined.
Original languageEnglish
Pages (from-to)1 - 21
Number of pages21
JournalCochrane Database of Systematic Reviews
Issue number2
DOIs
Publication statusPublished - 2007

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