Gold-catalyzed cycloisomerization and Diels-Alder reaction of 1,6-diyne esters with alkenes and diazenes to hydronaphthalenes and -cinnolines

Jianming Yan, Guan Liang Tay, Cuien Neo, Bo Ra Lee, Philip Wai Hong Chan

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Abstract

A method for the efficient preparation of hydronaphthalene and -cinnoline derivatives by Au(I)-catalyzed cycloisomerzation of 1,6-diyne esters followed by a Diels-Alder reaction with alkenes or diazenes under mild conditions at room temperature with catalyst loadings as low as 1 mol % is described
Original languageEnglish
Pages (from-to)4176-4179
Number of pages4
JournalOrganic Letters
Volume17
Issue number17
DOIs
Publication statusPublished - 2015

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