Gold-Catalyzed Aminoalkenylation of β-Amino-1,n-Diynols to Cycloalkyl-, Piperidinyl- and Pyranyl-Fused Pyrroles

Prasath Kothandaraman, Yichao Zhao, Bo Ra Lee, Clarrisa Jia Le Ng, Jun Yi Lee, Benjamin James Ayers, Philip Wai Hong Chan

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15 Citations (Scopus)

Abstract

A synthetic method to prepare cycloalkyl-, piperidinyl- and pyranyl-fused pyrroles efficiently by gold(I)-catalyzed dehydrative aminoalkenylation of β-amino-1,n-diynols under mild conditions at room temperature is described.

Original languageEnglish
Pages (from-to)1385-1391
Number of pages7
JournalAdvanced Synthesis and Catalysis
Volume358
Issue number9
DOIs
Publication statusPublished - 28 Apr 2016

Keywords

  • 1,2-amino alcohols
  • gold
  • homogeneous catalysis
  • nitrogen heterocycles
  • synthetic methods

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