Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 38 - 42 |
| Number of pages | 5 |
| Journal | Agro Food Industry Hi-Tech |
| Volume | 25 |
| Issue number | 2 |
| Publication status | Published - 2014 |
Cite this
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Gluten sensitivity without coeliac disease - a new twist. / Peters, Simone Louise; Muir, Jane Grey; Gibson, Peter Raymond.
In: Agro Food Industry Hi-Tech, Vol. 25, No. 2, 2014, p. 38 - 42.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Gluten sensitivity without coeliac disease - a new twist
AU - Peters, Simone Louise
AU - Muir, Jane Grey
AU - Gibson, Peter Raymond
PY - 2014
Y1 - 2014
N2 - Gluten-containing products are often blamed for contributing to various gastrointestinal and extraintestinal symptoms. While coeliac disease is a well-established entity, our understanding of non-coeliac gluten sensitivity (NCGS) is limited. Issues confounding progress in NCGS include the limited recognition of dietary components that often co-exist with gluten that might be triggering symptoms, lack of understanding of the mechanisms by which gluten might induce problems, and problems with clinical trial design and subsequent interpretation of results. A recent controlled trial using gold-standard elimination-rechallenge methodology in patients with self-reported NCGS has failed to confirm a gluten-specific effect on gastrointestinal symptoms. Furthermore, mechanisms by which gluten triggers symptoms remain unidentified. It is suggested that patients with suspected NCGS should explore other dietary triggers before exploring the gluten-free diet as an option.
AB - Gluten-containing products are often blamed for contributing to various gastrointestinal and extraintestinal symptoms. While coeliac disease is a well-established entity, our understanding of non-coeliac gluten sensitivity (NCGS) is limited. Issues confounding progress in NCGS include the limited recognition of dietary components that often co-exist with gluten that might be triggering symptoms, lack of understanding of the mechanisms by which gluten might induce problems, and problems with clinical trial design and subsequent interpretation of results. A recent controlled trial using gold-standard elimination-rechallenge methodology in patients with self-reported NCGS has failed to confirm a gluten-specific effect on gastrointestinal symptoms. Furthermore, mechanisms by which gluten triggers symptoms remain unidentified. It is suggested that patients with suspected NCGS should explore other dietary triggers before exploring the gluten-free diet as an option.
UR - http://www.teknoscienze.com/articles/agro-food-industry-hi-tech-gluten-sensitivity-without-coeliac-disease-ndash-a-new-twist.aspx#.VL3K40eUd8F
M3 - Article
VL - 25
SP - 38
EP - 42
JO - Agro Food Industry Hi-Tech
JF - Agro Food Industry Hi-Tech
SN - 1722-6996
IS - 2
ER -