Gluten causes gastrointestinal symptoms in subjects without celiac disease: a double blind randomized placebo-controlled trial

Jessica Rose Biesiekierski; Evan Newnham; Peter Irving; Jacqueline Barrett; Melissa Haines; James D Doecke; Susan Shepherd; Jane Muir; Peter Gibson

doi:10.1038/ajg.2010.487

Gluten causes gastrointestinal symptoms in subjects without celiac disease: a double blind randomized placebo-controlled trial

Jessica Rose Biesiekierski, Evan Newnham, Peter Irving, Jacqueline Barrett, Melissa Haines, James D Doecke, Susan Shepherd, Jane Muir, Peter Gibson

Eastern Health Clinical School

Research output: Contribution to journal › Article › Research › peer-review

519 Citations (Scopus)

Abstract

Despite increased prescription of a gluten-free diet for gastrointestinal symptoms in individuals who do not have celiac disease, there is minimal evidence that suggests that gluten is a trigger. The aims of this study were to determine whether gluten ingestion can induce symptoms in non-celiac individuals and to examine the mechanism.

Original language	English
Pages (from-to)	508 - 514
Number of pages	7
Journal	The American Journal of Gastroenterology
Volume	103
Issue number	3
DOIs	https://doi.org/10.1038/ajg.2010.487
Publication status	Published - 2011

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Biesiekierski, Jessica Rose ; Newnham, Evan ; Irving, Peter ; Barrett, Jacqueline ; Haines, Melissa ; Doecke, James D ; Shepherd, Susan ; Muir, Jane ; Gibson, Peter. / Gluten causes gastrointestinal symptoms in subjects without celiac disease: a double blind randomized placebo-controlled trial. In: The American Journal of Gastroenterology. 2011 ; Vol. 103, No. 3. pp. 508 - 514.

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Gluten causes gastrointestinal symptoms in subjects without celiac disease: a double blind randomized placebo-controlled trial. / Biesiekierski, Jessica Rose; Newnham, Evan; Irving, Peter; Barrett, Jacqueline; Haines, Melissa; Doecke, James D; Shepherd, Susan; Muir, Jane ; Gibson, Peter.

In: The American Journal of Gastroenterology, Vol. 103, No. 3, 2011, p. 508 - 514.

Research output: Contribution to journal › Article › Research › peer-review

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