Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study

Pil Seok Chae; Rohini R. Rana; Kamil Gotfryd; Søren G F Rasmussen; Andrew C. Kruse; Kyung Ho Cho; Stefano Capaldi; Emil Carlsson; Brian Kobilka; Claus J. Loland; Ulrik Gether; Surajit Banerjee; Bernadette Byrne; John K. Lee; Samuel H. Gellman

doi:10.1039/c2cc36844g

Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study

Pil Seok Chae, Rohini R. Rana, Kamil Gotfryd, Søren G F Rasmussen, Andrew C. Kruse, Kyung Ho Cho, Stefano Capaldi, Emil Carlsson, Brian Kobilka, Claus J. Loland, Ulrik Gether, Surajit Banerjee, Bernadette Byrne, John K. Lee, Samuel H. Gellman

Research output: Contribution to journal › Article › Research › peer-review

75 Citations (Scopus)

Abstract

The development of a new class of surfactants for membrane protein manipulation, "GNG amphiphiles", is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473).

Original language	English
Pages (from-to)	2287-2289
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	23
DOIs	https://doi.org/10.1039/c2cc36844g
Publication status	Published - 21 Mar 2013
Externally published	Yes

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title = "Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study",

abstract = "The development of a new class of surfactants for membrane protein manipulation, {"}GNG amphiphiles{"}, is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473).",

author = "Chae, {Pil Seok} and Rana, {Rohini R.} and Kamil Gotfryd and Rasmussen, {S{\o}ren G F} and Kruse, {Andrew C.} and Cho, {Kyung Ho} and Stefano Capaldi and Emil Carlsson and Brian Kobilka and Loland, {Claus J.} and Ulrik Gether and Surajit Banerjee and Bernadette Byrne and Lee, {John K.} and Gellman, {Samuel H.}",

year = "2013",

month = mar,

day = "21",

doi = "10.1039/c2cc36844g",

language = "English",

volume = "49",

pages = "2287--2289",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "The Royal Society of Chemistry",

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T1 - Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study

AU - Chae, Pil Seok

AU - Rana, Rohini R.

AU - Gotfryd, Kamil

AU - Rasmussen, Søren G F

AU - Kruse, Andrew C.

AU - Cho, Kyung Ho

AU - Capaldi, Stefano

AU - Carlsson, Emil

AU - Kobilka, Brian

AU - Loland, Claus J.

AU - Gether, Ulrik

AU - Banerjee, Surajit

AU - Byrne, Bernadette

AU - Lee, John K.

AU - Gellman, Samuel H.

PY - 2013/3/21

Y1 - 2013/3/21

N2 - The development of a new class of surfactants for membrane protein manipulation, "GNG amphiphiles", is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473).

AB - The development of a new class of surfactants for membrane protein manipulation, "GNG amphiphiles", is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473).

UR - http://www.scopus.com/inward/record.url?scp=84874820949&partnerID=8YFLogxK

U2 - 10.1039/c2cc36844g

DO - 10.1039/c2cc36844g

M3 - Article

AN - SCOPUS:84874820949

SN - 1359-7345

VL - 49

SP - 2287

EP - 2289

JO - Chemical Communications

JF - Chemical Communications

IS - 23

ER -

Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study

Abstract

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