TY - JOUR
T1 - Giving propranolol tablets to infants with hemangiomas - solubility in water
AU - Greenhill, Neil
AU - Deacon, Glen
AU - Phillips, Roderic
PY - 2011
Y1 - 2011
N2 - The discovery that propranolol can be an effective treatment for
infantile hemangiomas1 is changing management protocols and
many questions about optimum treatment plans are yet to be
answered. We have used propranolol to treat 150 infants with a
variety of hemangiomas. Babies commonly require doses of between 3 mg and 10 mg. Propranolol is sold commercially as
10 mg and 40 mg tablets. A propranolol syrup can be made up
by some pharmacies. However, this has a relatively short shelf
life and, unless it is subsidised (e.g. by a hospital), it can greatly
increase the cost. For example, families have paid 60a?? 70 per
month for syrup compared with 6 per month for tablets. For
this reason, most of our parents dissolve 10 mg tablets in water
and then withdraw the appropriate dose for the baby.
AB - The discovery that propranolol can be an effective treatment for
infantile hemangiomas1 is changing management protocols and
many questions about optimum treatment plans are yet to be
answered. We have used propranolol to treat 150 infants with a
variety of hemangiomas. Babies commonly require doses of between 3 mg and 10 mg. Propranolol is sold commercially as
10 mg and 40 mg tablets. A propranolol syrup can be made up
by some pharmacies. However, this has a relatively short shelf
life and, unless it is subsidised (e.g. by a hospital), it can greatly
increase the cost. For example, families have paid 60a?? 70 per
month for syrup compared with 6 per month for tablets. For
this reason, most of our parents dissolve 10 mg tablets in water
and then withdraw the appropriate dose for the baby.
UR - http://onlinelibrary.wiley.com.ezproxy.lib.monash.edu.au/doi/10.1111/j.1440-1754.2011.02135.x/pdf
U2 - 10.1111/j.1440-1754.2011.02135.x
DO - 10.1111/j.1440-1754.2011.02135.x
M3 - Letter
VL - 47
SP - 484
EP - 485
JO - Journal of Paediatrics and Child Health
JF - Journal of Paediatrics and Child Health
SN - 1034-4810
IS - 7
ER -