Germinal centers: A second childhood for lymphocytes

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Abstract

Recent observations show that, in the peripheral lymphoid organs known as germinal centers, lymphocytes appear to regain the phenotypic and molecular traits of immature cells; this cellular regression may play an important role in the affinity maturation of immune responses.

Original languageEnglish
JournalCurrent Biology
Volume7
Issue number3
Publication statusPublished - 1 Jan 1997

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