Germ granules and the control of mRNA translation

Madhu S Sengupta, Peter R Boag

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Abstract

Germ granules are an evolutionarily conserved feature of germ cell cytoplasm and are critical for gametogenesis and embryonic development. Germ granules are highly enriched for RNA and RNA-binding proteins and are key centers for post-transcriptional gene regulation in germ cells. Over the last 20 years, the molecular events in germ granule function and formation in several organisms have begun to be revealed. This review seeks to give an overview of some conserved features of germ granules and highlights a conserved strategy for regulating translation of maternal mRNAs. (c) 2012 IUBMB IUBMB Life, 64(7): 586-594, 2012.
Original languageEnglish
Pages (from-to)586 - 594
Number of pages9
JournalIUBMB Life
Volume64
Issue number7
DOIs
Publication statusPublished - 2012

Cite this