TY - JOUR
T1 - Genotypic diversity of coagulase-negative staphylococci causing endocarditis
T2 - A global perspective
AU - Petti, Cathy A.
AU - Simmon, Keith E.
AU - Miro, Jose M.
AU - Hoen, Bruno
AU - Marco, Francesc
AU - Chu, Vivian H.
AU - Athan, Eugene
AU - Bukovski, Suzana
AU - Bouza, Emilio
AU - Bradley, Suzanne
AU - Fowler, Vance G.
AU - Giannitsioti, Efthymia
AU - Gordon, David
AU - Reinbott, Porl
AU - Korman, Tony
AU - Lang, Selwyn
AU - Garcia-de-la-Maria, Cristina
AU - Raglio, Annibale
AU - Morris, Arthur J.
AU - Plesiat, Patrick
AU - Ryan, Suzanne
AU - Doco-Lecompte, Thanh
AU - Tripodi, Francesca
AU - Utili, Riccardo
AU - Wray, Dannah
AU - Federspiel, J. Jeffrey
AU - Boisson, K.
AU - Reller, L. Barth
AU - Murdoch, David R.
AU - Woods, Christopher W.
PY - 2008/5
Y1 - 2008/5
N2 - Coagulase-negative staphylococci (CNS) are important causes of infective endocarditis (IE), but their microbiological profiles are poorly described. We performed DNA target sequencing and susceptibility testing for 91 patients with definite CNS IE who were identified from the International Collaboration on Endocarditis - Microbiology, a large, multicenter, multinational consortium. A hierarchy of gene sequences demonstrated great genetic diversity within CNS from patients with definite endocarditis that represented diverse geographic regions. In particular, rpoB sequence data demonstrated unique genetic signatures with the potential to serve as an important tool for global surveillance.
AB - Coagulase-negative staphylococci (CNS) are important causes of infective endocarditis (IE), but their microbiological profiles are poorly described. We performed DNA target sequencing and susceptibility testing for 91 patients with definite CNS IE who were identified from the International Collaboration on Endocarditis - Microbiology, a large, multicenter, multinational consortium. A hierarchy of gene sequences demonstrated great genetic diversity within CNS from patients with definite endocarditis that represented diverse geographic regions. In particular, rpoB sequence data demonstrated unique genetic signatures with the potential to serve as an important tool for global surveillance.
UR - http://www.scopus.com/inward/record.url?scp=43249089113&partnerID=8YFLogxK
U2 - 10.1128/JCM.02405-07
DO - 10.1128/JCM.02405-07
M3 - Review Article
C2 - 18367572
AN - SCOPUS:43249089113
VL - 46
SP - 1780
EP - 1784
JO - Journal of Clinical Microbiology
JF - Journal of Clinical Microbiology
SN - 0095-1137
IS - 5
ER -