Genome sequence of Streptomyces pluripotens MUSC 135T exhibiting antibacterial and antioxidant activity

Ser Hooi Leng, Wen Si Tan, Nurul-Syakima Ab Mutalib, Huey Jia Cheng, Wai Fong Yin, Kok Gan Chan, Lee Learn Han

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    Isolated from intertidal soil, Streptomyces pluripotens MUSC 135T produces a broad-spectrum bacteriocin against the pathogens methicillin-resistant Staphylococcus aureus (MRSA) ATCC BAA-44T, Salmonella typhi ATCC 19430T and Aeromonas hydrophila ATCC 7966T. Along with antibacterial activity, fermentation studies on strain MUSC 135T revealed production of antioxidant(s). The high quality draft genome of MUSC 135T comprises 7,480,269bp with G+C content of 70.00 . Through bioinformatics analysis, 72 gene clusters identified in the genome were associated with the production of secondary metabolites, which may shed light on the identity of these bioactive compounds.
    Original languageEnglish
    Pages (from-to)281 - 283
    Number of pages3
    JournalMarine Genomics
    Publication statusPublished - 2015

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