TY - JOUR
T1 - Genetic variation in the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway affects contact hypersensitivity responses
AU - Legrand, Julien M.D.
AU - Roy, Edwige
AU - Baz, Batoul
AU - Mukhopadhyay, Pamela
AU - Wong, Ho Yi
AU - Ram, Ramesh
AU - Morahan, Grant
AU - Walker, Graeme
AU - Khosrotehrani, Kiarash
PY - 2018/9
Y1 - 2018/9
N2 - Using a genetic resource that enables rapid mapping of genes for complex traits, we demonstrate dramatic diversity between murine strains in response to immune challenge. We identified several candidate genes that point to the MAPK/ERK pathway as a key modulator of this process.
AB - Using a genetic resource that enables rapid mapping of genes for complex traits, we demonstrate dramatic diversity between murine strains in response to immune challenge. We identified several candidate genes that point to the MAPK/ERK pathway as a key modulator of this process.
UR - https://www.scopus.com/pages/publications/85048319442
U2 - 10.1016/j.jaci.2018.04.028
DO - 10.1016/j.jaci.2018.04.028
M3 - Article
SN - 0091-6749
VL - 142
SP - 981
EP - 984
JO - Journal of Allergy and Clinical Immunology
JF - Journal of Allergy and Clinical Immunology
IS - 3
ER -