Genetic variation in the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway affects contact hypersensitivity responses

Julien M.D. Legrand, Edwige Roy, Batoul Baz, Pamela Mukhopadhyay, Ho Yi Wong, Ramesh Ram, Grant Morahan, Graeme Walker, Kiarash Khosrotehrani

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Abstract

Using a genetic resource that enables rapid mapping of genes for complex traits, we demonstrate dramatic diversity between murine strains in response to immune challenge. We identified several candidate genes that point to the MAPK/ERK pathway as a key modulator of this process.
Original languageEnglish
Pages (from-to)981-984
Number of pages4
JournalJournal of Allergy and Clinical Immunology
Volume142
Issue number3
DOIs
Publication statusPublished - Sep 2018

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