Genetic analysis of K88-mediated adhesion of enterotoxigenic Escherichia coli

Michael Kehoe; Richard Sellwood; Patricia Shipley; Gordon Dougan

doi:10.1038/291122a0

Genetic analysis of K88-mediated adhesion of enterotoxigenic Escherichia coli

Michael Kehoe, Richard Sellwood, Patricia Shipley, Gordon Dougan

Research output: Contribution to journal › Article › Research › peer-review

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Abstract

Four cistrons (adh) involved in the expression of the K88 adhesion system have been identified and mapped. Three of these (adh A, adh B and adh C) are located in a single operon(I) whereas the fourth (adh D) is expressed from a separate promoter (operon II). The polypeptides encoded by these cistrons have been identified and their role in the formation and regulation of K88 fimbriae (pili) is discussed.

Original language	English
Pages (from-to)	122-126
Number of pages	5
Journal	Nature
Volume	291
Issue number	5811
DOIs	https://doi.org/10.1038/291122a0
Publication status	Published - 1 Dec 1981
Externally published	Yes

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title = "Genetic analysis of K88-mediated adhesion of enterotoxigenic Escherichia coli",

abstract = "Four cistrons (adh) involved in the expression of the K88 adhesion system have been identified and mapped. Three of these (adh A, adh B and adh C) are located in a single operon(I) whereas the fourth (adh D) is expressed from a separate promoter (operon II). The polypeptides encoded by these cistrons have been identified and their role in the formation and regulation of K88 fimbriae (pili) is discussed.",

author = "Michael Kehoe and Richard Sellwood and Patricia Shipley and Gordon Dougan",

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T1 - Genetic analysis of K88-mediated adhesion of enterotoxigenic Escherichia coli

AU - Kehoe, Michael

AU - Sellwood, Richard

AU - Shipley, Patricia

AU - Dougan, Gordon

PY - 1981/12/1

Y1 - 1981/12/1

N2 - Four cistrons (adh) involved in the expression of the K88 adhesion system have been identified and mapped. Three of these (adh A, adh B and adh C) are located in a single operon(I) whereas the fourth (adh D) is expressed from a separate promoter (operon II). The polypeptides encoded by these cistrons have been identified and their role in the formation and regulation of K88 fimbriae (pili) is discussed.

AB - Four cistrons (adh) involved in the expression of the K88 adhesion system have been identified and mapped. Three of these (adh A, adh B and adh C) are located in a single operon(I) whereas the fourth (adh D) is expressed from a separate promoter (operon II). The polypeptides encoded by these cistrons have been identified and their role in the formation and regulation of K88 fimbriae (pili) is discussed.

UR - https://www.scopus.com/pages/publications/0019830486

U2 - 10.1038/291122a0

DO - 10.1038/291122a0

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JO - Nature

JF - Nature

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ER -

Genetic analysis of K88-mediated adhesion of enterotoxigenic Escherichia coli

Abstract

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