Genetic analysis of K88-mediated adhesion of enterotoxigenic Escherichia coli

Michael Kehoe, Richard Sellwood, Patricia Shipley, Gordon Dougan

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48 Citations (Scopus)

Abstract

Four cistrons (adh) involved in the expression of the K88 adhesion system have been identified and mapped. Three of these (adh A, adh B and adh C) are located in a single operon(I) whereas the fourth (adh D) is expressed from a separate promoter (operon II). The polypeptides encoded by these cistrons have been identified and their role in the formation and regulation of K88 fimbriae (pili) is discussed.

Original languageEnglish
Pages (from-to)122-126
Number of pages5
JournalNature
Volume291
Issue number5811
DOIs
Publication statusPublished - 1 Dec 1981
Externally publishedYes

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