Generation of urine iPS cell line from a patient with obsessive-compulsive disorder using a non-integrative method

Jaroslaw Sochacki, Sylvie Devalle, Marcelo Reis, Leonardo F. Fontenelle, Stevens Rehen

Research output: Contribution to journalArticleOtherpeer-review

4 Citations (Scopus)

Abstract

Urine sample was collected from a 29-year-old male patient with an early onset form of DSM-5 obsessive-compulsive disorder (OCD), comorbid body dysmorphic and excoriation (skin-picking) disorders, and a positive family history for OCD. Urine cell line was established and expanded for the reprogramming procedure. Induced pluripotent stem (iPS) cells were derived using the integration-free CytoTune®-iPS 2.0 Sendai Reprogramming Kit, which includes Sendai virus particles of the four Yamanaka factors Oct3/4, Sox2, Klf4 and c-Myc.

Original languageEnglish
Pages (from-to)107-110
Number of pages4
JournalStem Cell Research
Volume17
Issue number1
DOIs
Publication statusPublished - 1 Jul 2016

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