Projects per year
Abstract
Peripheral blood mononuclear cells were donated by a male teenager with clinically diagnosed attention deficit hyperactivity disorder (ADHD) under the Diagnostic and Statistical Manual of Mental Disorders IV criteria and his unaffected male sibling. Induced pluripotent stem cells were developed using integration-free Sendai Reprogramming factors containing OCT4, SOX2, KLF4, and c-MYC. All four iPSC lines displayed pluripotent cell morphology, pluripotency-associated factors at the DNA and protein level, alkaline phosphatase enzymatic activity and a male karyotype of 46, XY. All lines had capacity for in vitro differentiation into all the three germ layers. All were negative for Mycoplasma.
Original language | English |
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Article number | 101353 |
Number of pages | 5 |
Journal | Stem Cell Research |
Volume | 34 |
DOIs | |
Publication status | Published - 1 Jan 2019 |
Projects
- 2 Finished
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Developing a pathophysiological model for Attention Deficit Hyperactivity Disorder: a path to biomarker discovery
Tong, J. (Primary Chief Investigator (PCI))
National Health and Medical Research Council (NHMRC) (Australia)
1/01/16 → 31/12/19
Project: Research
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Centre of Research Excellence for patient blood management in critical illness and trauma
Cooper, J. (Primary Chief Investigator (PCI)), Bellomo, R. (Chief Investigator (CI)), Cameron, P. (Chief Investigator (CI)), French, C. J. (Chief Investigator (CI)), Isbister, J. P. (Chief Investigator (CI)), McNeil, J. (Chief Investigator (CI)), Myles, P. (Chief Investigator (CI)), Phillips, L. (Chief Investigator (CI)), Reade, M. (Chief Investigator (CI)) & Webb, S. (Chief Investigator (CI))
National Health and Medical Research Council (NHMRC) (Australia)
1/11/12 → 31/10/18
Project: Research