'Generalizability' of a radial-aortic transfer function for the derivation of central aortic waveform parameters

Sarah Hope, Ian Meredith, David Tay, James Cameron

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Abstract

Arterial transfer functions (TFs) describe the relationship between the pressure waveform at different arterial sites. Generalized TFs are used to reconstruct central aortic waveforms from non-invasively obtained peripheral waveforms and have been promoted as potentially clinically useful. A limitation is the paucity of information on their generalizability with no information existing on the number of subjects required to construct a satisfactory TF, nor is adequate prospective validation available. We therefore investigated the uniformity of radial-aortic TFs and prospectively estimated the capacity of a generalized TF to reconstruct individual central blood pressure parameters.
Original languageEnglish
Pages (from-to)1812 - 1820
Number of pages9
JournalJournal of Hypertension
Volume25
Issue number9
DOIs
Publication statusPublished - 2007

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