Gene-environment interaction

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Abstract

Gene-environment interactions shape the development of phenotypes. Effects have been documented across outcomes as diverse and complex as clinical disorders and disease. Whilst some phenotypes may be shaped by genes more than environment or vice-versa, research has demonstrated the existence of an interaction. However, it has proven difficult to study the gene-environment interaction of complex outcomes such as intelligence and behavior. This is due to issues including insufficient capturing of environmental factors, the restrictive selection criteria of genes chosen for investigation, the need for large sample sizes, and the biological mechanisms that modify gene-environment interactions.

Original languageEnglish
Title of host publicationThe Wiley Encyclopedia of Personality and Individual Differences
Subtitle of host publicationModels and Theories
EditorsBernardo J Carducci, Christopher S Nave, Jeffrey S Mio, Ronald E Riggio
Place of PublicationHoboken NJ USA
PublisherWiley-Academy
Chapter37
Pages221-223
Number of pages3
Volume1
ISBN (Electronic)9781119547143
ISBN (Print)9781118970744, 9781119057505
DOIs
Publication statusPublished - 2020
Externally publishedYes

Keywords

  • Gene
  • Genetic polymorphisms
  • Genotype
  • Heritability
  • Phenotype

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