TY - JOUR
T1 - Gene Aging Nexus
T2 - A web database and data mining platform for microarray data on aging
AU - Pan, Fei
AU - Chiu, Chi Hsien
AU - Pulapura, Sudip
AU - Mehan, Michael R.
AU - Nunez-Iglesias, Juan
AU - Zhang, Kangyu
AU - Kamath, Kiran
AU - Waterman, Michael S.
AU - Finch, Caleb E.
AU - Zhou, Xianghong Jasmine
PY - 2007/1/1
Y1 - 2007/1/1
N2 - The recent development of microarray technology provided unprecedented opportunities to understand the genetic basis of aging. So far, many microarray studies have addressed aging-related expression patterns in multiple organisms and under different conditions. The number of relevant studies continues to increase rapidly. However, efficient exploitation of these vast data is frustrated by the lack of an integrated data mining platform or other unifying bioinformatic resource to enable convenient cross-laboratory searches of array signals. To facilitate the integrative analysis of microarray data on aging, we developed a web database and analysis platform 'Gene Aging Nexus' (GAN) that is freely accessible to the research community to query/analyze/ visualize cross-platform and cross-species microarray data on aging. By providing the possibility of integrative microarray analysis, GAN should be useful in building the systems-biology understanding of aging. GAN is accessible at http://gan.usc.edu.
AB - The recent development of microarray technology provided unprecedented opportunities to understand the genetic basis of aging. So far, many microarray studies have addressed aging-related expression patterns in multiple organisms and under different conditions. The number of relevant studies continues to increase rapidly. However, efficient exploitation of these vast data is frustrated by the lack of an integrated data mining platform or other unifying bioinformatic resource to enable convenient cross-laboratory searches of array signals. To facilitate the integrative analysis of microarray data on aging, we developed a web database and analysis platform 'Gene Aging Nexus' (GAN) that is freely accessible to the research community to query/analyze/ visualize cross-platform and cross-species microarray data on aging. By providing the possibility of integrative microarray analysis, GAN should be useful in building the systems-biology understanding of aging. GAN is accessible at http://gan.usc.edu.
UR - http://www.scopus.com/inward/record.url?scp=33846112971&partnerID=8YFLogxK
U2 - 10.1093/nar/gkl798
DO - 10.1093/nar/gkl798
M3 - Article
C2 - 17090592
AN - SCOPUS:33846112971
SN - 0305-1048
VL - 35
JO - Nucleic Acids Research
JF - Nucleic Acids Research
ER -