Gastrointestinal dysmotility: clinical consequences and management of the critically ill patient.

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Gastrointestinal dysmotility is a common feature of critical illness, with a number of significant implications that include malnutrition secondary to reduced feed tolerance and absorption, reflux and aspiration resulting in reduced lung function and ventilator-associated pneumonia, bacterial overgrowth and possible translocation causing nosocomial sepsis. Prokinetic agent administration can improve gastric emptying and caloric delivery, but its effect on nutrient absorption and clinical outcomes is, as yet, unclear. Postpyloric delivery of nutrition has not yet been demonstrated to increase caloric intake or improve clinical outcomes.

Original languageEnglish
Pages (from-to)725-739
Number of pages15
JournalGastroenterology Clinics of North America
Issue number4
Publication statusPublished - Dec 2011
Externally publishedYes


  • Critical illness
  • Enteral feeding
  • Gastric emptying
  • Gastrointestinal motility
  • Nutrient absorption
  • Prokinetic

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