Gastric procesing is a critical determinant of the ability of lipid-based formulations to enhance the oral bioavailability of a model poorly water-soluble drug

Kathy Wai-Yu Lee; Christopher John Porter; Benjamin James Boyd

Gastric procesing is a critical determinant of the ability of lipid-based formulations to enhance the oral bioavailability of a model poorly water-soluble drug

Kathy Wai-Yu Lee, Christopher John Porter, Benjamin James Boyd

Drug Delivery Disposition & Dynamics

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review

Abstract

The contribution of gastric processing of lipid-based formulations for poorly water soluble drugs was assessed via comparison between oral and intraduodenal administration. The data of plasma profiles suggest that both the type of lipid and gastric processing are critical to enhance the oral bioavailability of highly lipophilic poorly water soluble drugs.

Original language	English
Title of host publication	36th Annual Meeting & Exposition of the Controlled Release Society
Place of Publication	USA
Publisher	Controlled Release Society
Pages	on cd - on cd
Number of pages	2
Publication status	Published - 2009
Event	Annual Meeting & Exposition of the Controlled Release Society 2009 - Bella Center Coppenhagen Denmark, USA Duration: 1 Jan 2009 → …

Conference

Conference	Annual Meeting & Exposition of the Controlled Release Society 2009
City	USA
Period	1/01/09 → …

Cite this

@inproceedings{0e42eded3d874b759be9e404aa2413b5,

title = "Gastric procesing is a critical determinant of the ability of lipid-based formulations to enhance the oral bioavailability of a model poorly water-soluble drug",

abstract = "The contribution of gastric processing of lipid-based formulations for poorly water soluble drugs was assessed via comparison between oral and intraduodenal administration. The data of plasma profiles suggest that both the type of lipid and gastric processing are critical to enhance the oral bioavailability of highly lipophilic poorly water soluble drugs.",

author = "Lee, {Kathy Wai-Yu} and Porter, {Christopher John} and Boyd, {Benjamin James}",

year = "2009",

language = "English",

pages = "on cd -- on cd",

booktitle = "36th Annual Meeting & Exposition of the Controlled Release Society",

publisher = "Controlled Release Society",

address = "United States of America",

note = "Annual Meeting & Exposition of the Controlled Release Society 2009 ; Conference date: 01-01-2009",

}

Lee, KW-Y, Porter, CJ & Boyd, BJ 2009, Gastric procesing is a critical determinant of the ability of lipid-based formulations to enhance the oral bioavailability of a model poorly water-soluble drug. in 36th Annual Meeting & Exposition of the Controlled Release Society. Controlled Release Society, USA, pp. on cd - on cd, Annual Meeting & Exposition of the Controlled Release Society 2009, USA, 1/01/09.

Gastric procesing is a critical determinant of the ability of lipid-based formulations to enhance the oral bioavailability of a model poorly water-soluble drug. / Lee, Kathy Wai-Yu; Porter, Christopher John ; Boyd, Benjamin James.
36th Annual Meeting & Exposition of the Controlled Release Society. USA: Controlled Release Society, 2009. p. on cd - on cd.

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review

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AU - Lee, Kathy Wai-Yu

AU - Porter, Christopher John

AU - Boyd, Benjamin James

PY - 2009

Y1 - 2009

N2 - The contribution of gastric processing of lipid-based formulations for poorly water soluble drugs was assessed via comparison between oral and intraduodenal administration. The data of plasma profiles suggest that both the type of lipid and gastric processing are critical to enhance the oral bioavailability of highly lipophilic poorly water soluble drugs.

AB - The contribution of gastric processing of lipid-based formulations for poorly water soluble drugs was assessed via comparison between oral and intraduodenal administration. The data of plasma profiles suggest that both the type of lipid and gastric processing are critical to enhance the oral bioavailability of highly lipophilic poorly water soluble drugs.

M3 - Conference Paper

SP - on cd - on cd

BT - 36th Annual Meeting & Exposition of the Controlled Release Society

PB - Controlled Release Society

CY - USA

T2 - Annual Meeting & Exposition of the Controlled Release Society 2009

Y2 - 1 January 2009

ER -