Gastric emptying is accelerated following laparoscopic Nissen fundoplication

M. Pacilli, Agostino Pierro, Keith J. Lindley, Joseph I. Curry, Simon Eaton

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Abstract

Aim of the Study: The effects on gastric motility following Nissen fundoplication in children are poorly documented. Some paediatric surgeons advocate additional procedures at the same time as fundoplication, such as a pyloroplasty, to enhance gastric emptying. The aim of this study was to determine whether laparoscopic Nissen fundoplication without pyloroplasty affects gastric emptying. Methods: Gastric emptying was measured before laparoscopic Nissen fundoplication in 8 children after ingestion of a standardised volume of milk for age mixed with 150 mg of 13C-octanoic acid. None of the patients had a gastrostomy insertion at the time of fundoplication and 2 patients had neurological impairment. Breath samples were collected by breathing into a mask at baseline and every 15 minutes up to 3 hours, and were analysed for 13CO2/12CO2 ratio by mass spectrometry. Gastric emptying time (t1/2) was derived from the curve of 13CO2/12CO2 ratio against time. The test was repeated in 6 children following Nissen fundoplication at the time of full feeds. Data are reported as mean ± SD and were analysed by the Mann-Whitney test. Results and Conclusions: There were 4 males and 4 females; mean age at surgery was 3.3 ± 3.0 years. Mean gastric emptying time was 59 ± 17 min prior to laparoscopic Nissen fundoplication and 45 ± 4 min following surgery (p = 0.03). Gastric emptying was accelerated in all except one patient. Gastric emptying for liquids is accelerated following Nissen fundoplication in children. Procedures aimed at improving gastric emptying time such as pyloroplasty or pyloromyotomy might not be justified at the time of laparoscopic Nissen fundoplication.

Original languageEnglish
Pages (from-to)395-397
Number of pages3
JournalEuropean Journal of Pediatric Surgery
Volume18
Issue number6
DOIs
Publication statusPublished - Dec 2008
Externally publishedYes

Keywords

  • Gastric emptying
  • Gastro-oesophageal reflux
  • Laparoscopy
  • Nissen fundoplication

Cite this

Pacilli, M. ; Pierro, Agostino ; Lindley, Keith J. ; Curry, Joseph I. ; Eaton, Simon. / Gastric emptying is accelerated following laparoscopic Nissen fundoplication. In: European Journal of Pediatric Surgery. 2008 ; Vol. 18, No. 6. pp. 395-397.
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abstract = "Aim of the Study: The effects on gastric motility following Nissen fundoplication in children are poorly documented. Some paediatric surgeons advocate additional procedures at the same time as fundoplication, such as a pyloroplasty, to enhance gastric emptying. The aim of this study was to determine whether laparoscopic Nissen fundoplication without pyloroplasty affects gastric emptying. Methods: Gastric emptying was measured before laparoscopic Nissen fundoplication in 8 children after ingestion of a standardised volume of milk for age mixed with 150 mg of 13C-octanoic acid. None of the patients had a gastrostomy insertion at the time of fundoplication and 2 patients had neurological impairment. Breath samples were collected by breathing into a mask at baseline and every 15 minutes up to 3 hours, and were analysed for 13CO2/12CO2 ratio by mass spectrometry. Gastric emptying time (t1/2) was derived from the curve of 13CO2/12CO2 ratio against time. The test was repeated in 6 children following Nissen fundoplication at the time of full feeds. Data are reported as mean ± SD and were analysed by the Mann-Whitney test. Results and Conclusions: There were 4 males and 4 females; mean age at surgery was 3.3 ± 3.0 years. Mean gastric emptying time was 59 ± 17 min prior to laparoscopic Nissen fundoplication and 45 ± 4 min following surgery (p = 0.03). Gastric emptying was accelerated in all except one patient. Gastric emptying for liquids is accelerated following Nissen fundoplication in children. Procedures aimed at improving gastric emptying time such as pyloroplasty or pyloromyotomy might not be justified at the time of laparoscopic Nissen fundoplication.",
keywords = "Gastric emptying, Gastro-oesophageal reflux, Laparoscopy, Nissen fundoplication",
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Gastric emptying is accelerated following laparoscopic Nissen fundoplication. / Pacilli, M.; Pierro, Agostino; Lindley, Keith J.; Curry, Joseph I.; Eaton, Simon.

In: European Journal of Pediatric Surgery, Vol. 18, No. 6, 12.2008, p. 395-397.

Research output: Contribution to journalArticleResearchpeer-review

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T1 - Gastric emptying is accelerated following laparoscopic Nissen fundoplication

AU - Pacilli, M.

AU - Pierro, Agostino

AU - Lindley, Keith J.

AU - Curry, Joseph I.

AU - Eaton, Simon

PY - 2008/12

Y1 - 2008/12

N2 - Aim of the Study: The effects on gastric motility following Nissen fundoplication in children are poorly documented. Some paediatric surgeons advocate additional procedures at the same time as fundoplication, such as a pyloroplasty, to enhance gastric emptying. The aim of this study was to determine whether laparoscopic Nissen fundoplication without pyloroplasty affects gastric emptying. Methods: Gastric emptying was measured before laparoscopic Nissen fundoplication in 8 children after ingestion of a standardised volume of milk for age mixed with 150 mg of 13C-octanoic acid. None of the patients had a gastrostomy insertion at the time of fundoplication and 2 patients had neurological impairment. Breath samples were collected by breathing into a mask at baseline and every 15 minutes up to 3 hours, and were analysed for 13CO2/12CO2 ratio by mass spectrometry. Gastric emptying time (t1/2) was derived from the curve of 13CO2/12CO2 ratio against time. The test was repeated in 6 children following Nissen fundoplication at the time of full feeds. Data are reported as mean ± SD and were analysed by the Mann-Whitney test. Results and Conclusions: There were 4 males and 4 females; mean age at surgery was 3.3 ± 3.0 years. Mean gastric emptying time was 59 ± 17 min prior to laparoscopic Nissen fundoplication and 45 ± 4 min following surgery (p = 0.03). Gastric emptying was accelerated in all except one patient. Gastric emptying for liquids is accelerated following Nissen fundoplication in children. Procedures aimed at improving gastric emptying time such as pyloroplasty or pyloromyotomy might not be justified at the time of laparoscopic Nissen fundoplication.

AB - Aim of the Study: The effects on gastric motility following Nissen fundoplication in children are poorly documented. Some paediatric surgeons advocate additional procedures at the same time as fundoplication, such as a pyloroplasty, to enhance gastric emptying. The aim of this study was to determine whether laparoscopic Nissen fundoplication without pyloroplasty affects gastric emptying. Methods: Gastric emptying was measured before laparoscopic Nissen fundoplication in 8 children after ingestion of a standardised volume of milk for age mixed with 150 mg of 13C-octanoic acid. None of the patients had a gastrostomy insertion at the time of fundoplication and 2 patients had neurological impairment. Breath samples were collected by breathing into a mask at baseline and every 15 minutes up to 3 hours, and were analysed for 13CO2/12CO2 ratio by mass spectrometry. Gastric emptying time (t1/2) was derived from the curve of 13CO2/12CO2 ratio against time. The test was repeated in 6 children following Nissen fundoplication at the time of full feeds. Data are reported as mean ± SD and were analysed by the Mann-Whitney test. Results and Conclusions: There were 4 males and 4 females; mean age at surgery was 3.3 ± 3.0 years. Mean gastric emptying time was 59 ± 17 min prior to laparoscopic Nissen fundoplication and 45 ± 4 min following surgery (p = 0.03). Gastric emptying was accelerated in all except one patient. Gastric emptying for liquids is accelerated following Nissen fundoplication in children. Procedures aimed at improving gastric emptying time such as pyloroplasty or pyloromyotomy might not be justified at the time of laparoscopic Nissen fundoplication.

KW - Gastric emptying

KW - Gastro-oesophageal reflux

KW - Laparoscopy

KW - Nissen fundoplication

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U2 - 10.1055/s-2008-1038919

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JO - European Journal of Pediatric Surgery

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SN - 0939-7248

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