Gallium-68 Prostate-specific Membrane Antigen Positron Emission Tomography in Advanced Prostate Cancer—Updated Diagnostic Utility, Sensitivity, Specificity, and Distribution of Prostate-specific Membrane Antigen-avid Lesions: A Systematic Review and Meta-analysis

Marlon Perera, Nathan Papa, Matthew Roberts, Michael Williams, Cristian Udovicich, Ian Vela, Daniel Christidis, Damien Bolton, Michael S. Hofman, Nathan Lawrentschuk, Declan G. Murphy

Research output: Contribution to journalReview ArticleResearchpeer-review

262 Citations (Scopus)

Abstract

Gallium-68 prostate-specific membrane antigen positron emission tomography is now an established imaging technique that has been developed in response to inadequacies in standard-of-care imaging modalities to improve the detection of metastatic disease in prostate cancer. In light of the growing body of evidence, we summarised the data to date to provide clinicians with an overview of this imaging modality.

Original languageEnglish
Pages (from-to)403-417
Number of pages15
JournalEuropean Urology
Volume77
Issue number4
DOIs
Publication statusPublished - Apr 2020
Externally publishedYes

Keywords

  • Biochemical recurrence
  • Imaging
  • Metastases
  • Positron emission tomography
  • Prostate cancer
  • Prostate-specific antigen
  • Prostate-specific membrane antigen
  • Sensitivity

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