Critically ill patients are increasingly treated with continuous hemofiltration and derived techniques, now grouped under the term of continuous renal replacement therapy (CRRT). CRRT can provide adequate blood purification and correction of electrolyte derangements. They also seem to prevent further injury to the patient by maintaining a stable level of homeostasis. Recently, newer indications have been proposed for CRRT, including the treatment of neonates, patients with heart disease, and septic patients. It has been hypothesized that continuous therapies might contribute to the removal of noxious substances in the middle molecular-weight range, such as cytokines or autocoids. According to these new indications, technical developments are making available new forms of treatment, new materials, and specially designed machines.
- acute renal failure
- continuous therapies