TY - JOUR
T1 - Functional interventions as augmentation strategies for obsessive-compulsive disorder (OCD)
T2 - scoping review and expert survey from the international college of obsessive-compulsive spectrum disorders (ICOCS)
AU - Varinelli, Alberto
AU - Caricasole, Valentina
AU - Pellegrini, Luca
AU - Hall, Natalie
AU - Garg, Kabir
AU - Mpavaenda, Davis
AU - Dell’Osso, Bernardo
AU - Albert, Umberto
AU - Van Ameringen, Michael
AU - Fontenelle, Leonardo
AU - Grassi, Giacomo
AU - Feusner, Jamie
AU - Carmi, Lior
AU - Grunblatt, Edna
AU - Walitza, Susanne
AU - Lochner, Christine
AU - Rodriguez, Carolyn
AU - Bystritsky, Alexander
AU - Rosario, Maria Ceica
AU - van Roessel, Peter
AU - Geller, Dan
AU - Hollander, Eric
AU - Nicolini, Humberto
AU - Zohar, Joseph
AU - Menchón, José
AU - the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) Expert Survey Workgroup
AU - Fineberg, Naomi A
N1 - Funding Information:
This paper and the research behind it would not have been possible without the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) (www.ICOCS.org), who have contributed, through providing networking opportunities, to the development of this work.
Publisher Copyright:
© 2021 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2022/3
Y1 - 2022/3
N2 - Background: Patients with obsessive-compulsive disorder (OCD) commonly exhibit a range of functional difficulties, presumed linked to neurocognitive changes. Evidence-based first-line treatments have limited effect on improving these cognitive-functional problems. Candidate interventions could be used to augment evidence-based treatments by the multi-professional mental health team. Methods: A scoping review was performed to identify any intervention with at least one peer-reviewed report of clinical improvement in any of the 13 functional domains of the Cognitive Assessment Instrument of Obsessions and Compulsions (CAIOC-13). Next, an online survey of experts of the International College of Obsessive-Compulsive Spectrum Disorders was conducted. Results: Forty-four studies were identified reporting a positive outcome for 27 different kinds of intervention. Twenty-six experts from 12 different countries, including at least one expert from each continent, completed the opinion survey. Five interventions were identified as ‘highly promising’, none of which was moderated by rater-related factors, suggesting global applicability. Conclusion: Patients with OCD may benefit from a detailed functional assessment, to identify areas of unmet need. A variety of interventions show theoretical promise for treating the complex functional difficulties in OCD as adjuncts to first-line treatments, but the published evidence is weak. Randomised controlled trials are needed to determine the clinical effectiveness of these interventions.Highlights Functional-cognitive problems are common in patients with OCD. First-line evidence-based treatments have limited effect on these functionalcognitive difficulties. In our scoping review we found 44 studies reporting of improved clinical outcomes in any of the 13 functional domains of the Cognitive Assessment Instrument of Obsessions and Compulsions (CAIOC-13). An online survey of experts of the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) was conducted and identified five interventions as “highly promising” candidate treatments for functional-cognitive problems in OCD. Randomised controlled trials are needed to determine the clinical effectiveness of these interventions.
AB - Background: Patients with obsessive-compulsive disorder (OCD) commonly exhibit a range of functional difficulties, presumed linked to neurocognitive changes. Evidence-based first-line treatments have limited effect on improving these cognitive-functional problems. Candidate interventions could be used to augment evidence-based treatments by the multi-professional mental health team. Methods: A scoping review was performed to identify any intervention with at least one peer-reviewed report of clinical improvement in any of the 13 functional domains of the Cognitive Assessment Instrument of Obsessions and Compulsions (CAIOC-13). Next, an online survey of experts of the International College of Obsessive-Compulsive Spectrum Disorders was conducted. Results: Forty-four studies were identified reporting a positive outcome for 27 different kinds of intervention. Twenty-six experts from 12 different countries, including at least one expert from each continent, completed the opinion survey. Five interventions were identified as ‘highly promising’, none of which was moderated by rater-related factors, suggesting global applicability. Conclusion: Patients with OCD may benefit from a detailed functional assessment, to identify areas of unmet need. A variety of interventions show theoretical promise for treating the complex functional difficulties in OCD as adjuncts to first-line treatments, but the published evidence is weak. Randomised controlled trials are needed to determine the clinical effectiveness of these interventions.Highlights Functional-cognitive problems are common in patients with OCD. First-line evidence-based treatments have limited effect on these functionalcognitive difficulties. In our scoping review we found 44 studies reporting of improved clinical outcomes in any of the 13 functional domains of the Cognitive Assessment Instrument of Obsessions and Compulsions (CAIOC-13). An online survey of experts of the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) was conducted and identified five interventions as “highly promising” candidate treatments for functional-cognitive problems in OCD. Randomised controlled trials are needed to determine the clinical effectiveness of these interventions.
KW - augmentation strategies
KW - functional interventions
KW - functional-cognitive problems
KW - ICOCS
KW - International College of Obsessive-Compulsive Spectrum Disorders
KW - Obsessive-compulsive disorder
UR - http://www.scopus.com/inward/record.url?scp=85110036433&partnerID=8YFLogxK
U2 - 10.1080/13651501.2021.1872646
DO - 10.1080/13651501.2021.1872646
M3 - Review Article
C2 - 33502269
AN - SCOPUS:85110036433
SN - 1365-1501
VL - 26
SP - 92
EP - 107
JO - International Journal of Psychiatry in Clinical Practice
JF - International Journal of Psychiatry in Clinical Practice
IS - 1
ER -