The prefrontal cortex (PFC) is thought to play crucial roles in higher cognitive functions, since it has largely evolved in primates. The primate PFC is composed of several areas that differ in their anatomical connections with other brain structures, such as sensory and motor association cortical areas, the basal ganglia, limbic structures, and the hypothalamus (Barbas, 2000; Fuster, 2008; Goldman-Rakic, 1987; Ongur Price, 2000). The functional divisions among prefrontal areas, however, remain largely unknown. We have examined the functional divisions in the primate PFC by comparing neuronal activities and lesion-behavior effects among different prefrontal areas. The elucidation of these functional subdivisions should allow us to understand apparently complicated cognitive functions in terms of more elementary processes. The functional divisions among prefrontal areas are also discussed in other chapters in this book, including Chapter 2, by Fuster; Chapter 14, by Watanabe; and Chapter 6, by Wallis and Kennerley.
|Title of host publication||Principles of Frontal Lobe Function|
|Editors||D T Stuss, R T Knight|
|Place of Publication||USA|
|Publisher||Oxford University Press, USA|
|Pages||1 - 50|
|Number of pages||50|
|Publication status||Published - 2013|