FTIR imaging of tissues: Techniques and methods of analysis

Kamilla Malek, Bayden R. Wood, Keith R. Bambery

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

22 Citations (Scopus)

Abstract

In this chapter, we describe biomedical applications of infrared microscopic imaging applied to human tissue sections. The central focus is human diseases including cervical cancer, neurodegenerative pathologies, and dysfunctions of cardiac and liver tissues. In addition, we briefly describe the fundamentals of FTIR imaging instrumentation along with spectral pre-processing and hyperspectral image reconstruction. The chapter concludes with a summary of what is required to take FTIR imaging technology into the clinical environment.

Original languageEnglish
Title of host publicationOptical Spectroscopy and Computational Methods in Biology and Medicine
EditorsMalgorzata Baranska
Place of PublicationGermany
PublisherSpringer-Praxis
Pages419-473
Number of pages55
ISBN (Electronic)9789400778320
ISBN (Print)9789400778313
DOIs
Publication statusPublished - 1 Jan 2014

Publication series

NameChallenges and Advances in Computational Chemistry and Physics
Volume14
ISSN (Print)2542-4491
ISSN (Electronic)2542-4483

Keywords

  • Cervical cancer
  • Data processing
  • FTIR imaging
  • Heart disease
  • Liver diseases
  • Neurodegenerative pathologies

Cite this

Malek, K., Wood, B. R., & Bambery, K. R. (2014). FTIR imaging of tissues: Techniques and methods of analysis. In M. Baranska (Ed.), Optical Spectroscopy and Computational Methods in Biology and Medicine (pp. 419-473). (Challenges and Advances in Computational Chemistry and Physics; Vol. 14). Germany: Springer-Praxis. https://doi.org/10.1007/978-94-007-7832-0_15