From BACs to drugs

Panos A Ioannou, Jim Vadolas, Joseph P Sarsero

Research output: Contribution to journalReview ArticleOtherpeer-review


Completion of the sequencing phase of the Human Genome Project and the availability of most genes as intact functional units in bacterial artificial chromosomes (PACs or BACs), provide a solid platform for development of drugs for the targeted modification of gene expression. Emerging techniques for precise engineering of human genes in bacterial artificial chromosomes are rapidly bringing this possibility closer to reality.
Original languageEnglish
Pages (from-to)46-48
Number of pages3
JournalToday's Life Science
Issue number1
Publication statusPublished - Jan 2002
Externally publishedYes

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